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ARB-272572 hydrochloride
😃Good
Catalog No. T83976Cas No. 2377524-19-9
Alias ARB-272572 hydrochloride（2368182-63-0 Free base）
ARB-272572 hydrochloride is a small molecule PD-L1 inhibitor with an IC50 value of 400 pM for PD-1/PD-L1 HTRF.ARB-272572 hydrochloride inhibits PD-1/PD-L1 cell signaling by inducing homologous interactions with PD-L1 proteins.
ARB-272572 hydrochloride
😃Good
Purity: 99%
Catalog No. T83976Alias ARB-272572 hydrochloride（2368182-63-0 Free base）Cas No. 2377524-19-9
ARB-272572 hydrochloride is a small molecule PD-L1 inhibitor with an IC50 value of 400 pM for PD-1/PD-L1 HTRF.ARB-272572 hydrochloride inhibits PD-1/PD-L1 cell signaling by inducing homologous interactions with PD-L1 proteins.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $195 | In Stock | |
| 25 mg | $1,080 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $39 | Backorder |
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Purity:99%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | ARB-272572 hydrochloride is a small molecule PD-L1 inhibitor with an IC50 value of 400 pM for PD-1/PD-L1 HTRF.ARB-272572 hydrochloride inhibits PD-1/PD-L1 cell signaling by inducing homologous interactions with PD-L1 proteins. |
| Alias | ARB-272572 hydrochloride（2368182-63-0 Free base） |
| Molecular Weight | 568.68(Free base） |
| Formula | C32H36N6O4.xClH |
| Cas No. | 2377524-19-9 |
| Smiles | Cl.O=C(NC1=CC=CC(C=2C=CC=C(NC(=O)C3=NC=C(C=C3)CNCCO)C2C)=C1C)C4=NC=C(C=C4)CNCCO xHCl |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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