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ATF3 inducer 1 is an efficient ATF3 inducer with lipid-lowering and anti-hyperglycemic activities. It alleviates glucose intolerance and insulin resistance induced by high-fat diet (HFD) and ameliorates liver steatosis induced by HFD. It can be used for research on obesity.
Pack Size | Price | Availability | Quantity |
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5 mg | $142 | In Stock |
Description | ATF3 inducer 1 is an efficient ATF3 inducer with lipid-lowering and anti-hyperglycemic activities. It alleviates glucose intolerance and insulin resistance induced by high-fat diet (HFD) and ameliorates liver steatosis induced by HFD. It can be used for research on obesity. |
In vitro | ATF3 inducer 1 (Compound 16c) (50 μM, treated for 8 days) upregulates the expression levels of ATF3 protein and ATF3 mRNA in 3T3-L1 cells. [1] |
In vivo | ATF3 inducer 1 (40 mg/kg, intraperitoneal injection, three times per week for 10 weeks) exhibited anti-metabolic syndrome (MetS) effects in mice. [1] |
Molecular Weight | 230.22 |
Formula | C12H10N2O3 |
Cas No. | 3038756-30-5 |
Smiles | O=C1OC=2C=C(OC)C=CC2C=3NN=C(C13)C |
Relative Density. | no data available |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (217.18 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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