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ATP dimagnesium

Name: ATP dimagnesium
Brand: TargetMol
SKU: T75325
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T75325Cas No. 74804-12-9

ATP dimagnesium is an important substance for energy storage and metabolism in the body and is involved in the energy cycle and metabolism of the body.ATP dimagnesium can act as a coenzyme in cells and can be used as a signaling molecule.

ATP dimagnesium

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Purity: 99.19%

Catalog No. T75325Cas No. 74804-12-9

Pack Size	Price	Availability	Quantity
50 mg	$30	In Stock
100 mg	$40	In Stock

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Purity:99.19%

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COA LCMS HNMR

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Product Introduction

Bioactivity

Description	ATP dimagnesium is an important substance for energy storage and metabolism in the body and is involved in the energy cycle and metabolism of the body.ATP dimagnesium can act as a coenzyme in cells and can be used as a signaling molecule.
In vitro	ATP dimagnesium (5 mM; 1h) and LPS (1 μg/mL) Co-treatment have a synergistic effect on the activation of NLRP3 inflammasome in HGFs.[3] ATP dimagnesium (2 mM; 0.5-24h) induces BMDM secretion of IL-1β, KC, and MIP-2 in a caspase-1 activation-dependent manner. ATP dimagnesium promotes neutrophil chemotaxis in vitro.[4]
In vivo	ATP dimagnesium (50 mg/kg;i.p.; Four-week-old Kunming mice) protected mice from bacterial infection in vivo. ATP dimagnesium induced the secretion of IL-1β, KC, and MIP-2 and neutrophil recruitment in vivo.[4]

Chemical Properties

Molecular Weight	551.76
Formula	C₁₀H₁₂Mg₂N₅O₁₃P₃
Cas No.	74804-12-9
Smiles	[Mg++].[Mg++].Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

H2O: 200 mg/mL (362.48 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.8124 mL	9.0619 mL	18.1238 mL	90.6191 mL
5 mM	0.3625 mL	1.8124 mL	3.6248 mL	18.1238 mL
10 mM	0.1812 mL	0.9062 mL	1.8124 mL	9.0619 mL
20 mM	0.0906 mL	0.4531 mL	0.9062 mL	4.5310 mL
50 mM	0.0362 mL	0.1812 mL	0.3625 mL	1.8124 mL
100 mM	0.0181 mL	0.0906 mL	0.1812 mL	0.9062 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc