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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $970 | 6-8 weeks | |
50 mg | $1,260 | 6-8 weeks | |
100 mg | $2,190 | 6-8 weeks |
Description | AZD3458 is a potent and remarkably selective inhibitor of PI3Kγ (PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ with pIC50s of 9.1, 5.1, <4.5, and 6.5 , respectively). |
In vivo | AZD3458 (Compound 15) is a potent and remarkably selective PI3Kγ inhibitor with ADME properties suitable for oral administration.?Compound 15 was advanced into in vivo studies showing dose-dependent inhibition of LPS-induced airway neutrophilia in rats when administered orally. |
Molecular Weight | 433.54 |
Formula | C20H23N3O4S2 |
Cas No. | 2132961-46-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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