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Azido-PEG2-azide

🥰Excellent
Catalog No. T17492Cas No. 59559-06-7

Azido-PEG2-azide, a PEG-based PROTAC linker, is utilized in PROTAC synthesis.

Azido-PEG2-azide

Azido-PEG2-azide

🥰Excellent
Purity: 100%
Catalog No. T17492Cas No. 59559-06-7
Azido-PEG2-azide, a PEG-based PROTAC linker, is utilized in PROTAC synthesis.
Pack SizePriceAvailabilityQuantity
25 mg$30In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Azido-PEG2-azide, a PEG-based PROTAC linker, is utilized in PROTAC synthesis.
In vitro
PROTACs consist of two distinct ligands joined by a linker: one targets an E3 ubiquitin ligase, and the other targets the specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Chemical Properties
Molecular Weight200.2
FormulaC6H12N6O2
Cas No.59559-06-7
Smiles[N-]=[N+]=NCCCOCOCCN=[N+]=[N-]
Relative Density.1.15 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (499.50 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.9950 mL24.9750 mL49.9500 mL249.7502 mL
5 mM0.9990 mL4.9950 mL9.9900 mL49.9500 mL
10 mM0.4995 mL2.4975 mL4.9950 mL24.9750 mL
20 mM0.2498 mL1.2488 mL2.4975 mL12.4875 mL
50 mM0.0999 mL0.4995 mL0.9990 mL4.9950 mL
100 mM0.0500 mL0.2498 mL0.4995 mL2.4975 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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