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DADPS Biotin Azide

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Purity:95%

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COA HNMR

DADPS Biotin Azide

Catalog No. T17582Cas No. 1260247-50-4

Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEGylated PROTAC linker suitable for PROTAC synthesis [1].

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Pack Size	Price	Availability
1 mg	$95	7-10 days
5 mg	$235	7-10 days
10 mg	$372	7-10 days
25 mg	$613	7-10 days

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Product Introduction

Bioactivity

Description	Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEGylated PROTAC linker suitable for PROTAC synthesis [1].
In vitro	PROTACs, comprising two distinct ligands linked by a connector—one binding to an E3 ubiquitin ligase and the other to the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Alias	Biotin-PEG4-amino-t-Bu-DADPS-C6-azide

Chemical Properties

Molecular Weight	886.18
Formula	C43H67N7O9SSi
Cas No.	1260247-50-4

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 80 mg/mL (90.28 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.1284 mL	5.6422 mL	11.2844 mL	56.4219 mL
5 mM	0.2257 mL	1.1284 mL	2.2569 mL	11.2844 mL
10 mM	0.1128 mL	0.5642 mL	1.1284 mL	5.6422 mL
20 mM	0.0564 mL	0.2821 mL	0.5642 mL	2.8211 mL
50 mM	0.0226 mL	0.1128 mL	0.2257 mL	1.1284 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc