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Biotin-PEG6-Boc (Biotin-PEG6-t-butyl ester) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $29 | In Stock | |
5 mg | $68 | In Stock | |
10 mg | $98 | In Stock | |
25 mg | $167 | In Stock | |
50 mg | $250 | In Stock | |
100 mg | $371 | In Stock | |
200 mg | $527 | In Stock |
Description | Biotin-PEG6-Boc (Biotin-PEG6-t-butyl ester) is a PEG-based PROTAC linker that can be used in PROTAC synthesis. |
In vitro | PROTACs consist of two ligands linked together, with one ligand targeting an E3 ubiquitin ligase and the other targeting the desired protein. They harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | Biotin-PEG6-t-butyl ester |
Molecular Weight | 635.81 |
Formula | C29H53N3O10S |
Cas No. | 1352814-07-3 |
Smiles | C(CCCC(NCCOCCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O)=O)[C@H]1[C@@]2([C@](CS1)(NC(=O)N2)[H])[H] |
Relative Density. | 1.136 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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