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BMS 199264 hydrochloride is the salt form of BMS 199264.BMS 199264 is a potent and selective inhibitor of mitochondrial F1F0 ATP hydrolase (IC50=0.5 μM) without affecting ATP synthetase, thus preventing ATP reduction to ameliorate cardiac necrosis during ischemia, and is commonly used in studies of the cardiovascular system.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $195 | Backorder | |
5 mg | $483 | Backorder | |
10 mg | $692 | Backorder | |
25 mg | $1,080 | Backorder | |
50 mg | $1,490 | Backorder | |
100 mg | $1,970 | Backorder | |
200 mg | $2,690 | Backorder |
Description | BMS 199264 hydrochloride is the salt form of BMS 199264.BMS 199264 is a potent and selective inhibitor of mitochondrial F1F0 ATP hydrolase (IC50=0.5 μM) without affecting ATP synthetase, thus preventing ATP reduction to ameliorate cardiac necrosis during ischemia, and is commonly used in studies of the cardiovascular system. |
In vitro | BMS 199264 (1-10 μM) preserves ATP in rat hearts during ischemia but does not affect pre-ischemic contractile function or ATP concentrations. BMS 199264 replenishes reperfusion ATP levels more rapidly and reduces necrosis. BMS 199264 selectively inhibits ATP hydrolase activity in vitro. [2] |
Alias | BMS199264 |
Molecular Weight | 531.07 |
Formula | C26H31ClN4O4S |
Cas No. | 675833-20-2 |
Smiles | N(CC=1NC=CN1)([C@@H]2C=3C(OC(C)(C)[C@H]2O)=CC=C(S(=O)(=O)N4CCCCC4)C3)C5=CC=C(Cl)C=C5 |
Relative Density. | no data available |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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