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BMS 199264

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Catalog No. T26843LCas No. 675833-20-2
Alias BMS199264

BMS 199264 hydrochloride is the salt form of BMS 199264.BMS 199264 is a potent and selective inhibitor of mitochondrial F1F0 ATP hydrolase (IC50=0.5 μM) without affecting ATP synthetase, thus preventing ATP reduction to ameliorate cardiac necrosis during ischemia, and is commonly used in studies of the cardiovascular system.

BMS 199264

BMS 199264

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Purity: 99.83%
Catalog No. T26843LAlias BMS199264Cas No. 675833-20-2
BMS 199264 hydrochloride is the salt form of BMS 199264.BMS 199264 is a potent and selective inhibitor of mitochondrial F1F0 ATP hydrolase (IC50=0.5 μM) without affecting ATP synthetase, thus preventing ATP reduction to ameliorate cardiac necrosis during ischemia, and is commonly used in studies of the cardiovascular system.
Pack SizePriceAvailabilityQuantity
1 mg$195 Backorder
5 mg$483 Backorder
10 mg$692 Backorder
25 mg$1,080 Backorder
50 mg$1,490 Backorder
100 mg$1,970 Backorder
200 mg$2,690 Backorder
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Purity:99.83%
ee:100%
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Product Introduction

Bioactivity
Description
BMS 199264 hydrochloride is the salt form of BMS 199264.BMS 199264 is a potent and selective inhibitor of mitochondrial F1F0 ATP hydrolase (IC50=0.5 μM) without affecting ATP synthetase, thus preventing ATP reduction to ameliorate cardiac necrosis during ischemia, and is commonly used in studies of the cardiovascular system.
In vitro
BMS 199264 (1-10 μM) preserves ATP in rat hearts during ischemia but does not affect pre-ischemic contractile function or ATP concentrations. BMS 199264 replenishes reperfusion ATP levels more rapidly and reduces necrosis. BMS 199264 selectively inhibits ATP hydrolase activity in vitro. [2]
AliasBMS199264
Chemical Properties
Molecular Weight531.07
FormulaC26H31ClN4O4S
Cas No.675833-20-2
SmilesN(CC=1NC=CN1)([C@@H]2C=3C(OC(C)(C)[C@H]2O)=CC=C(S(=O)(=O)N4CCCCC4)C3)C5=CC=C(Cl)C=C5
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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