Shopping Cart
- Remove All
Your shopping cart is currently empty
Boc-NH-PEG4-CH2CH2COOH
😃Good
Catalog No. T14006Cas No. 756525-91-4
Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTAC[1] and as a cleavable ADC linker for antibody-drug conjugates (ADC)[2].
Boc-NH-PEG4-CH2CH2COOH
😃Good
Catalog No. T14006Cas No. 756525-91-4
Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTAC[1] and as a cleavable ADC linker for antibody-drug conjugates (ADC)[2].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 mg | Inquiry | 7-10 days | |
| 500 mg | Inquiry | 7-10 days |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Boc-NH-PEG4-CH2CH2COOH"
Succinic anhydride
T18723108-30-5
Succinic anhydride is a cyclic anhydride. Succinic anhydride acts as a nonclaevable ADC linker. Succinic anhydride can react with compound 4 to link the prodrug to an amine or hydroxy 1 group of a targeting polypeptide.
- $29
Size
QTY
EMCS
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
T1406155750-63-5
EMCS (6-Maleimidohexanoic acid N-hydroxysuccinimide ester) is a heterobifunctional crosslinking agent, which is a compound for the preparation of hapten conjugate and enzyme immune conjugate, and an effective protective group in antibody drug conjugate.
- $46
Size
QTY
Fmoc-8-amino-3,6-dioxaoctanoic acid
Fmoc-NH-PEG2-CH2COOH
T15304166108-71-0
Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and a PEG-based PROTAC linker for the synthesis of PROTACs.
- $29
Size
QTY
DSG Crosslinker
T1517179642-50-5
DSG Crosslinker, a cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs).
- $39
Size
QTY
Fmoc-Gly-Gly-OH
T1795235665-38-4
Fmoc-Gly-Gly-OH, a cleavable ADC linker, can be used in the synthesis of antibody-drug conjugates (ADCs).
- $30
Size
QTY
DSS Crosslinker
T1517668528-80-3
DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is a homobifunctional crosslinker that is cell membrane permeable, with amine-reactive NHS esters at both ends of an 8-atom [11.4 angstrom] spacer arm for conjugating proteins, including intracellular proteins.
- $41
Size
QTY
SMCC
N-Succinimidyl 4-(N-maleimidomethyl)cycl
T911664987-85-5
SMCC (N-Succinimidyl 4-(N-maleimidomethyl)cycl) is a heterobifunctional protein crosslinker.
- $30
Size
QTY
Boc-NH-PEG4-CH2COOH
T14746876345-13-0
Boc-NH-PEG4-CH2COOH is a cleavable ADC linker utilized in the development of antibody-drug conjugates (ADC)[1].
- $29
Size
QTY
DSP Crosslinker
Cited
T1517557757-57-0
DSP Crosslinker, used in antibody-drug conjugates (ADCs) synthesis, is a cleavable ADC linker[1].
- $30
Size
QTY
CitedVal-cit-PAB-OH
T17213159857-79-1
Val-cit-PAB-OH is an ADC linker that is cleavable.
- $29
Size
QTY
FMoc-Val-Cit-PAB-PNP
T7767863971-53-3
Fmoc-Val-Cit-PAB-PNP is a linker used in Antibody-Drug Conjugation (ADC).
- $116
Size
QTY
N-Boc-PEG5-bromide
T162181392499-32-9
N-Boc-PEG5-bromide is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and serves as a PROTAC linker based on PEG and Alkyl/ether.
- $29
Size
QTY
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTAC[1] and as a cleavable ADC linker for antibody-drug conjugates (ADC)[2]. |
| In vitro | PROTACs, or proteolysis-targeting chimeras, are composed of two distinct ligands joined by a linker. One of these ligands binds to a specific protein target, while the other binds to an E3 ubiquitin ligase. When the PROTAC binds to both the target protein and the E3 ligase, it triggers the ubiquitin-proteasome system within cells to degrade the target protein, thereby providing a mechanism for targeted protein degradation. |
| Molecular Weight | 365.42 |
| Formula | C16H31NO8 |
| Cas No. | 756525-91-4 |
| Relative Density. | 1.124±0.06 g/cm3 (20°C 760 Torr) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Boc-NH-PEG4-CH2CH2COOH | purchase Boc-NH-PEG4-CH2CH2COOH | Boc-NH-PEG4-CH2CH2COOH cost | order Boc-NH-PEG4-CH2CH2COOH | Boc-NH-PEG4-CH2CH2COOH chemical structure | Boc-NH-PEG4-CH2CH2COOH in vitro | Boc-NH-PEG4-CH2CH2COOH formula | Boc-NH-PEG4-CH2CH2COOH molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.