Popular Searches
Diphenyleneiodonium chlorideEpacadostatGilteritinibDinaciclibRo-3306
TargetMol | Star Product
Wikimole
TargetMol | New Product
New Product
TargetMol | Compound Library
Compound Library
Contact Us
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
TOPBioactivityChemical infoStorage&SolubilityCalculator

Brr2-IN-3

🥰Excellent
Catalog No. T22282Cas No. 2104030-82-0
Alias Brr2 Inhibitor C9, Brr2 Inhibitor 9

Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa (a group of progressive retinal degenerative disorders).

Brr2-IN-3

Brr2-IN-3

🥰Excellent
Purity: 99.26%
Catalog No. T22282Alias Brr2 Inhibitor C9, Brr2 Inhibitor 9Cas No. 2104030-82-0
Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa (a group of progressive retinal degenerative disorders).
Pack SizePriceAvailabilityQuantity
1 mg$46In Stock
2 mg$63In Stock
5 mg$98In Stock
10 mg$173In Stock
25 mg$323In Stock
50 mg$467In Stock
100 mg$653In Stock
200 mg$879In Stock
1 mL x 10 mM (in DMSO)$118In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "Brr2-IN-3"

Select Batch
Purity:99.26%
Contact us for more batch information
Resource Download
COA HPLC HNMR LCMS
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa (a group of progressive retinal degenerative disorders).
Targets&IC50
BRR2:1.3 μM (IC50)
AliasBrr2 Inhibitor C9, Brr2 Inhibitor 9
Chemical Properties
Molecular Weight444.51
FormulaC24H20N4O3S
Cas No.2104030-82-0
SmilesO=C1Nc2cc(=O)n(Cc3ccccc3)cc2CN1c1cccc(OCc2cncs2)c1
Relative Density.1.44 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 27.5 mg/mL (61.87 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2497 mL11.2483 mL22.4967 mL112.4834 mL
5 mM0.4499 mL2.2497 mL4.4993 mL22.4967 mL
10 mM0.2250 mL1.1248 mL2.2497 mL11.2483 mL
20 mM0.1125 mL0.5624 mL1.1248 mL5.6242 mL
50 mM0.0450 mL0.2250 mL0.4499 mL2.2497 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

targetingspliceosomal RNA helicase Brr2selectivepotentInhibitorinhibithelicasedose-dependentBrr2-IN-3Brr-2-IN-3Brr2IN3Brr2 IN 3allosteric
Related Tags: buy Brr2-IN-3 | purchase Brr2-IN-3 | Brr2-IN-3 cost | order Brr2-IN-3 | Brr2-IN-3 chemical structure | Brr2-IN-3 formula | Brr2-IN-3 molecular weight
TargetMol | Logo

Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.