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Bruceantinol

🥰Excellent
Catalog No. TN1453Cas No. 53729-52-5

Bruceantinol has antiviral activity, it can inhibit pepper mottle virus in pepper; it shows antibabesial activity against Babesia gibsoni in vitro, with the IC50 value of 12 ng/mL.

Bruceantinol

Bruceantinol

🥰Excellent
Purity: 99.52%
Catalog No. TN1453Cas No. 53729-52-5
Bruceantinol has antiviral activity, it can inhibit pepper mottle virus in pepper; it shows antibabesial activity against Babesia gibsoni in vitro, with the IC50 value of 12 ng/mL.
Pack SizePriceAvailabilityQuantity
1 mg$168In Stock
5 mg$420In Stock
10 mg$623In Stock
25 mg$993In Stock
50 mg$1,330In Stock
100 mg$1,780In Stock
1 mL x 10 mM (in DMSO)$640In Stock
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Purity:99.52%
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Product Introduction

Bioactivity
Description
Bruceantinol has antiviral activity, it can inhibit pepper mottle virus in pepper; it shows antibabesial activity against Babesia gibsoni in vitro, with the IC50 value of 12 ng/mL.
In vitro
A green fluorescent protein (GFP)-tagged pepper mottle virus (PepMoV) based leaf-disc method and systemic host method were developed to identify antiviral agents. Preliminary experiments using a PepMoV-GFP based leaf-disc method led to the isolation of five quassinoids, including brusatol (1), bruceantin (2), brucein A (3), Bruceantinol (4), and brucein B (5), from the CH3OH extract of Brucea javanica[1]
Chemical Properties
Molecular Weight606.61
FormulaC30H38O13
Cas No.53729-52-5
Smiles[H][C@]12[C@@H](OC(=O)\C=C(/C)C(C)(C)OC(C)=O)C(=O)O[C@]3([H])C[C@@]4([H])C(C)=C(O)C(=O)C[C@]4(C)[C@@]4([H])[C@@H](O)[C@H](O)[C@]1(OC[C@@]234)C(=O)OC
Relative Density.1.43 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (90.67 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6485 mL8.2425 mL16.4851 mL82.4253 mL
5 mM0.3297 mL1.6485 mL3.2970 mL16.4851 mL
10 mM0.1649 mL0.8243 mL1.6485 mL8.2425 mL
20 mM0.0824 mL0.4121 mL0.8243 mL4.1213 mL
50 mM0.0330 mL0.1649 mL0.3297 mL1.6485 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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