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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $293 | In Stock | |
5 mg | $719 | In Stock | |
10 mg | $987 | In Stock | |
25 mg | $1,490 | In Stock | |
50 mg | $1,980 | In Stock | |
100 mg | $2,750 | In Stock |
Description | Candoxatril (UK 79300) is an orally active neutral peptide endonuclease (NEP, EC 3.4.24.11) inhibitor that improves exercise capacity in patients with chronic heart failure undergoing angiotensin-converting enzyme inhibition. |
In vivo | Although NEP inhibitors have no significant effect on body weight, food and water intake, mean blood pressure or creatinine levels, they do increase urinary cGMP levels and affect hematopoiesis in an anti-inflammatory manner. Furthermore, a-SMA deposition in the renal cortex is inversely correlated with elevated cGMP [2]. |
Alias | UK 79300 |
Molecular Weight | 515.64 |
Formula | C29H41NO7 |
Cas No. | 123122-55-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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