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Candoxatril

Catalog No. T10671Cas No. 123122-55-4
Alias UK 79300

Candoxatril (UK 79300) is an orally active neutral peptide endonuclease (NEP, EC 3.4.24.11) inhibitor that improves exercise capacity in patients with chronic heart failure undergoing angiotensin-converting enzyme inhibition.

Candoxatril

Candoxatril

Purity: 99.56%
Catalog No. T10671Alias UK 79300Cas No. 123122-55-4
Candoxatril (UK 79300) is an orally active neutral peptide endonuclease (NEP, EC 3.4.24.11) inhibitor that improves exercise capacity in patients with chronic heart failure undergoing angiotensin-converting enzyme inhibition.
Pack SizePriceAvailabilityQuantity
1 mg$293In Stock
5 mg$719In Stock
10 mg$987In Stock
25 mg$1,490In Stock
50 mg$1,980In Stock
100 mg$2,7507-10 days
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Purity:99.56%
ee:99.14%
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Product Introduction

Bioactivity
Description
Candoxatril (UK 79300) is an orally active neutral peptide endonuclease (NEP, EC 3.4.24.11) inhibitor that improves exercise capacity in patients with chronic heart failure undergoing angiotensin-converting enzyme inhibition.
In vivo
NEP inhibitors do not significantly affect body weight, food and water intake, mean blood pressure, or creatinine levels; however, they increase cGMP levels in urine and exhibit anti-inflammatory effects on hematopoiesis. Additionally, a-SMA deposition in the kidney cortex is inversely correlated with cGMP elevation [2].
AliasUK 79300
Chemical Properties
Molecular Weight515.64
FormulaC29H41NO7
Cas No.123122-55-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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