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Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $39 | In Stock | |
100 mg | $59 | In Stock | |
200 mg | $86 | In Stock | |
1 mL x 10 mM (in DMSO) | $39 | In Stock |
Description | Cbz-NH-PEG1-CH2COOH, a PEG-based PROTAC linker, is utilized in PROTAC synthesis. |
In vitro | PROTACs consist of two ligands linked together: one binds to an E3 ubiquitin ligase and the other to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs enable the selective degradation of target proteins[2]. |
Molecular Weight | 253.25 |
Formula | C12H15NO5 |
Cas No. | 1260092-43-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (394.87 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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