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CHDI 00484077 is a highly selective, central nervous system (CNS) permeable Class IIa HDAC inhibitor with inhibitory effects on HDAC4, HDAC5, HDAC7, and HDAC9, which improves neuronal function, and can be used to study Huntington's disease.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $187 | In Stock | |
5 mg | $463 | In Stock | |
10 mg | $678 | In Stock | |
25 mg | $1,070 | In Stock | |
50 mg | $1,430 | In Stock | |
100 mg | $1,930 | In Stock | |
200 mg | $2,620 | In Stock |
Description | CHDI 00484077 is a highly selective, central nervous system (CNS) permeable Class IIa HDAC inhibitor with inhibitory effects on HDAC4, HDAC5, HDAC7, and HDAC9, which improves neuronal function, and can be used to study Huntington's disease. |
Targets&IC50 | HDAC2:27 μM, HDAC3:10 μM, HDAC8:2 μM, HDAC6:22 μM, HDAC1:17 μM, HDAC5:0.02 μM, HDAC7:0.02 μM, HDAC9:0.03 μM, HDAC4:0.01 μM |
Alias | CHDI00484077 |
Molecular Weight | 382.38 |
Formula | C18H21F3N4O2 |
Cas No. | 3025894-92-9 |
Smiles | C(F)(F)(F)C1=NC(=NO1)C2=CC=C(C(N[C@@H](CN3[C@@H](C)CCC3)C)=O)C=C2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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