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CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $65 | In Stock | |
5 mg | $130 | In Stock | |
10 mg | $211 | In Stock | |
25 mg | $337 | In Stock | |
50 mg | $461 | In Stock | |
100 mg | $592 | In Stock | |
200 mg | $783 | In Stock | |
1 mL x 10 mM (in DMSO) | $173 | In Stock |
Description | CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia. |
Targets&IC50 | CRTH2:≤10 nM |
In vitro | CRTH2, also known as GPR44(chemoattractant receptor-homologous molecule expressed on Th2 cells) protein, is a G-protein coupled receptor (GPCR) which is amongst other ligands most strongly activated by prostaglandin D2 (PGD2). PGD2 is a product of prostaglandin D2 synthase (PTGDS)[1]. |
Molecular Weight | 474.94 |
Formula | C26H23ClN4O3 |
Cas No. | 780763-95-3 |
Smiles | CN(C)c1nc(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)nc(Cl)c1CC(O)=O |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45 mg/mL (94.75 mM) ![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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