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CRTh2 antagonist 2

🥰Excellent
Catalog No. T10889Cas No. 780763-95-3

CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.

CRTh2 antagonist 2

CRTh2 antagonist 2

🥰Excellent
Purity: 99.53%
Catalog No. T10889Cas No. 780763-95-3
CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.
Pack SizePriceAvailabilityQuantity
1 mg$65In Stock
5 mg$130In Stock
10 mg$211In Stock
25 mg$337In Stock
50 mg$461In Stock
100 mg$592In Stock
200 mg$783In Stock
1 mL x 10 mM (in DMSO)$173In Stock
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Purity:99.53%
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Product Introduction

Bioactivity
Description
CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.
Targets&IC50
CRTH2:≤10 nM
In vitro
CRTH2, also known as GPR44(chemoattractant receptor-homologous molecule expressed on Th2 cells) protein, is a G-protein coupled receptor (GPCR) which is amongst other ligands most strongly activated by prostaglandin D2 (PGD2). PGD2 is a product of prostaglandin D2 synthase (PTGDS)[1].
Chemical Properties
Molecular Weight474.94
FormulaC26H23ClN4O3
Cas No.780763-95-3
SmilesCN(C)c1nc(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)nc(Cl)c1CC(O)=O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (94.75 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1055 mL10.5276 mL21.0553 mL105.2765 mL
5 mM0.4211 mL2.1055 mL4.2111 mL21.0553 mL
10 mM0.2106 mL1.0528 mL2.1055 mL10.5276 mL
20 mM0.1053 mL0.5264 mL1.0528 mL5.2638 mL
50 mM0.0421 mL0.2106 mL0.4211 mL2.1055 mL

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