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CSN5-IN-1 (compound Ac-11) serves as an inhibitor of CSN5, exhibiting IC50 values of 12.56 μM in FP assay and 19 μM in fluorescence assay. Additionally, it influences cellular protein expression by downregulating PD-L1 and upregulating NEDD8-Cul1.
Pack Size | Price | Availability | Quantity |
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10 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | CSN5-IN-1 (compound Ac-11) serves as an inhibitor of CSN5, exhibiting IC50 values of 12.56 μM in FP assay and 19 μM in fluorescence assay. Additionally, it influences cellular protein expression by downregulating PD-L1 and upregulating NEDD8-Cul1. |
Molecular Weight | 318.43 |
Formula | C17H22N2O2S |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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