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Cyclen

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Catalog No. TJS1183Cas No. 294-90-6
Alias 1,4,7,10-tetraazacyclododecane

Cyclen (1,4,7,10-tetraazacyclododecane) is a macrocycle capable of selectively binding cations that used as a ligand in chemistry for instance with chemicals used in MRI contrast agents.

Cyclen

Cyclen

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Catalog No. TJS1183Alias 1,4,7,10-tetraazacyclododecaneCas No. 294-90-6
Cyclen (1,4,7,10-tetraazacyclododecane) is a macrocycle capable of selectively binding cations that used as a ligand in chemistry for instance with chemicals used in MRI contrast agents.
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Product Introduction

Bioactivity
Description
Cyclen (1,4,7,10-tetraazacyclododecane) is a macrocycle capable of selectively binding cations that used as a ligand in chemistry for instance with chemicals used in MRI contrast agents.
Alias1,4,7,10-tetraazacyclododecane
Chemical Properties
Molecular Weight172.27
FormulaC8H20N4
Cas No.294-90-6
SmilesC1CNCCNCCNCCN1
Relative Density.1.13 Corresponds to D4(20). Temperature:20 °C.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: < 1 mg/mL (insoluble)
H2O: 197.4 mM
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM5.8048 mL29.0242 mL58.0484 mL290.2421 mL
5 mM1.1610 mL5.8048 mL11.6097 mL58.0484 mL
10 mM0.5805 mL2.9024 mL5.8048 mL29.0242 mL
20 mM0.2902 mL1.4512 mL2.9024 mL14.5121 mL
50 mM0.1161 mL0.5805 mL1.1610 mL5.8048 mL
100 mM0.0580 mL0.2902 mL0.5805 mL2.9024 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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