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DBCO-PEG4-NHS ester is a PEG-based PROTAC linker utilized in PROTAC synthesis[1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $59 | In Stock | |
5 mg | $147 | In Stock | |
10 mg | $247 | In Stock | |
25 mg | $418 | In Stock | |
50 mg | $596 | In Stock | |
100 mg | $863 | In Stock | |
1 mL x 10 mM (in DMSO) | $215 | In Stock |
Description | DBCO-PEG4-NHS ester is a PEG-based PROTAC linker utilized in PROTAC synthesis[1]. |
In vitro | PROTACs consist of two ligands linked together: one ligand targets an E3 ubiquitin ligase, and the other targets the specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 649.69 |
Formula | C34H39N3O10 |
Cas No. | 1427004-19-0 |
Smiles | O=C(CCC(=O)N1Cc2ccccc2C#Cc2ccccc12)NCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O |
Relative Density. | 1.33 g/cm3 (Predicted) |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 79 mg/mL (121.59 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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