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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $129 | In Stock | |
5 mg | $289 | In Stock | |
10 mg | $455 | In Stock | |
25 mg | $753 | In Stock | |
50 mg | $1,060 | In Stock | |
100 mg | $1,430 | In Stock |
Description | dTRIM24 is a selective bifunctional TRIM24 degradation agent based on PROTAC technology, consisting of the ligands von Hippel-Lindau and TRIM24. |
In vitro | dTRIM24 suppresses growth, accompanied by apoptosis measured as enhanced PARP cleavage.[1] dTRIM24 is a TRIM24 bromodomain degrader.[1] Recruitment of the VHL E3 ubiquitin ligase by dTRIM24 elicits potent and selective degradation of TRIM24.[1] |
Molecular Weight | 1113.3 |
Formula | C55H68N8O13S2 |
Cas No. | 2170695-14-2 |
Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | Ethanol: insoluble DMSO: 90.0 mg/mL (80.8 mM ), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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