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Dulozafone

Catalog No. T68058Cas No. 75616-02-3
Alias F1933

Dulozafone (F1933) has an anti- showed anticonvulsant activity in a brain amygdala ignition model and protected fully ignited rats from generalized seizures.

Dulozafone

Dulozafone

Purity: 98.77%
Catalog No. T68058Alias F1933Cas No. 75616-02-3
Dulozafone (F1933) has an anti- showed anticonvulsant activity in a brain amygdala ignition model and protected fully ignited rats from generalized seizures.
Pack SizePriceAvailabilityQuantity
1 mg$191In Stock
5 mg$480In Stock
10 mg$687In Stock
25 mg$1,080In Stock
50 mg$1,480In Stock
100 mg$1,990In Stock
500 mg$3,920In Stock
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Purity:98.77%
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Product Introduction

Bioactivity
Description
Dulozafone (F1933) has an anti- showed anticonvulsant activity in a brain amygdala ignition model and protected fully ignited rats from generalized seizures.
In vivo
Dulozafone (F1933) protected fully kindled rats against generalized seizures but failed to suppress partial ictal events (amygdala after discharges and limbic seizures). The anticonvulsive action of F1933, administered at the ED100, was nearly reversed by the specific antagonist of benzodiazepine receptors; R015-1788 (Flumazenil), suggesting that the effect of F1933 is mediated by this receptor. These results also emphasize the usefulness of kindling to test antiepileptic drugs and to confirm their supposed profile of action.[1]
AliasF1933
Chemical Properties
Molecular Weight425.31
FormulaC20H22Cl2N2O4
Cas No.75616-02-3
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 60 mg/mL (141.07 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3512 mL11.7561 mL23.5123 mL117.5613 mL
5 mM0.4702 mL2.3512 mL4.7025 mL23.5123 mL
10 mM0.2351 mL1.1756 mL2.3512 mL11.7561 mL
20 mM0.1176 mL0.5878 mL1.1756 mL5.8781 mL
50 mM0.0470 mL0.2351 mL0.4702 mL2.3512 mL
100 mM0.0235 mL0.1176 mL0.2351 mL1.1756 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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