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EGFR-IN-16
Catalog No. T8525Cas No. 133550-22-8
Alias AG473
EGFR-IN-16 (AG473) is an inhibitor of EGFR in human A431 cells.
EGFR-IN-16
Catalog No. T8525Alias AG473Cas No. 133550-22-8
EGFR-IN-16 (AG473) is an inhibitor of EGFR in human A431 cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $122 | 6-8 weeks | |
| 10 mg | $195 | 6-8 weeks | |
| 25 mg | $370 | 6-8 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | EGFR-IN-16 (AG473) is an inhibitor of EGFR in human A431 cells. |
| In vivo | Expressed the EGFR-IN-16 lipoprotein from Neisseria meningitides, flagellin FlaB from Vibrio vulnificus and heat shock protein 70 from Mycobacterium tuberculosis (mHsp70) in Escherichia coli as single proteins and fusion proteins with VP2 protein of infectious bursal disease virus (IBDV).Both cellular and humoral adjuvanticities of the three TLR ligands were compared by immunization of mice in two different ways.Among the three co-administered TLR ligands, recombinant EGFR-IN-16 lipoprotein exhibited the highest cellular and humoral adjuvanticities, including promotion of IL-4, IL-12, IFN-γ and IBDV VP2-specific antibody production.Among the three genetically fused TLR ligands, fusion with EGFR-IN-16 D1 domain exhibited the highest cellular and humoral adjuvanticities. |
| Alias | AG473 |
| Molecular Weight | 265.26 |
| Formula | C16H11NO3 |
| Cas No. | 133550-22-8 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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