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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | EGFR/CDK2-IN-3 (compound 4b) serves as a dual inhibitor targeting both EGFR and CDK-2, exhibiting IC50 values of 71.7 nM and 113.7 nM, respectively. It prompts apoptosis in MCF-7 cells and halts the cell cycle in the S phase while demonstrating substantial anti-cancer cell toxicity, inhibiting MCF-7 cells with an IC50 of 3.16 μM [1]. |
Molecular Weight | 512.58 |
Formula | C30H20N6OS |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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