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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $148 | In Stock | |
5 mg | $368 | In Stock | |
10 mg | $550 | In Stock | |
25 mg | $887 | In Stock | |
50 mg | $1,220 | In Stock | |
1 mL x 10 mM (in DMSO) | $390 | In Stock |
Description | Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside has anti-inflammatory activities and also may have significant therapeutic benefits against diabetic complications and atherosclerosis. |
In vitro | Emodin-6-O-β-D-glucoside (EG) is a new active compound from Reynoutria japonica. EG was found to suppress the release of HMGB1, the production of tumor necrosis factor (TNF)-α, and the activation of nuclear factor-κB (NF-κB) by HMGB1 in HUVECs |
In vivo | Emodin-6-O-β-D-glucoside (EG) also inhibit HMGB1-mediated hyperpermeability and leukocyte migration in mice. Furthermore, EG also increased the survival times of CLP administered mice. |
Alias | Glucoemodin |
Molecular Weight | 432.38 |
Formula | C21H20O10 |
Cas No. | 34298-85-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 65 mg/ml (150.33 mM) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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