Popular Searches
Diphenyleneiodonium chlorideEpacadostatGilteritinibDinaciclibRo-3306
TargetMol | Star Product
Wikimole
TargetMol | New Product
New Product
TargetMol | Compound Library
Compound Library
Contact Us
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
TOPBioactivityChemical infoStorage&SolubilityCalculator

Emodin 6-O-β-D-glucoside

Catalog No. TN6774Cas No. 34298-85-6
Alias Glucoemodin

Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside has anti-inflammatory activities and also may have significant therapeutic benefits against diabetic complications and atherosclerosis.

Emodin 6-O-β-D-glucoside

Emodin 6-O-β-D-glucoside

Purity: 97.61%
Catalog No. TN6774Alias GlucoemodinCas No. 34298-85-6
Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside has anti-inflammatory activities and also may have significant therapeutic benefits against diabetic complications and atherosclerosis.
Pack SizePriceAvailabilityQuantity
1 mg$73In Stock
5 mg$179In Stock
10 mg$289In Stock
25 mg$489In Stock
1 mL x 10 mM (in DMSO)$212In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "Emodin 6-O-β-D-glucoside"

Select Batch
Purity:97.61%
Contact us for more batch information
Resource Download
COA HNMR HPLC
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside has anti-inflammatory activities and also may have significant therapeutic benefits against diabetic complications and atherosclerosis.
In vitro
Emodin-6-O-β-D-glucoside (EG), a novel active compound from Reynoutria japonica, suppresses HMGB1 release, TNF-α production, and HMGB1-induced NF-κB activation in HUVECs.
In vivo
Emodin-6-O-β-D-glucoside (EG) inhibits HMGB1-mediated hyperpermeability and leukocyte migration in mice, and increases the survival times of CLP-administered mice.
AliasGlucoemodin
Chemical Properties
Molecular Weight432.38
FormulaC21H20O10
Cas No.34298-85-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 65 mg/ml (150.33 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3128 mL11.5639 mL23.1278 mL115.6390 mL
5 mM0.4626 mL2.3128 mL4.6256 mL23.1278 mL
10 mM0.2313 mL1.1564 mL2.3128 mL11.5639 mL
20 mM0.1156 mL0.5782 mL1.1564 mL5.7820 mL
50 mM0.0463 mL0.2313 mL0.4626 mL2.3128 mL
100 mM0.0231 mL0.1156 mL0.2313 mL1.1564 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

atherosclerosisEmodin 6OβDglucosideEmodin 6-O-beta-D-glucosidediabeticReynoutriaactiveInhibitorEmodin 6-O-b-D-glucosideEmodin 6-O-β-D-glucosidebarriercomplicationspotentjaponicaprotectiveanti-inflammatoryEmodin 6 O β D glucosideinhibit
Related Tags: buy Emodin 6-O-β-D-glucoside | purchase Emodin 6-O-β-D-glucoside | Emodin 6-O-β-D-glucoside cost | order Emodin 6-O-β-D-glucoside | Emodin 6-O-β-D-glucoside chemical structure | Emodin 6-O-β-D-glucoside in vivo | Emodin 6-O-β-D-glucoside in vitro | Emodin 6-O-β-D-glucoside formula | Emodin 6-O-β-D-glucoside molecular weight
TargetMol | Logo

Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.