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Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2 that strengthens immunity by regulating cathelicidin antimicrobial peptide (CAMP) and defensin β-4 (DEFB4) genes in normal and transformed cells, combating pathogenic infections.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $97 | In Stock | |
5 mg | $437 | In Stock | |
10 mg | $648 | In Stock | |
25 mg | $987 | In Stock | |
50 mg | Inquiry | In Stock |
Description | Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2 that strengthens immunity by regulating cathelicidin antimicrobial peptide (CAMP) and defensin β-4 (DEFB4) genes in normal and transformed cells, combating pathogenic infections. |
In vivo | Ercalcitriol binds to vitamin D receptor (VDR), a nuclear receptor, activates the interaction between VDR and retinol X receptor (RXR) to form VDR/RXR/ cofactor complex, which binds to Vitamin D response elements in the promoter region of target genes to regulate gene transcription[3]. |
Alias | 1α,25-Dihydroxy Vitamin D2 |
Molecular Weight | 428.65 |
Formula | C28H44O3 |
Cas No. | 60133-18-8 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45.0 mg/mL (105.0 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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