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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $97 | In Stock | |
5 mg | $437 | In Stock | |
10 mg | $648 | In Stock | |
25 mg | $987 | In Stock | |
50 mg | Inquiry | In Stock |
Description | Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2. Ercalcitriol, as the physiological activated form of vitamin D, can strengthen immunity via regulation of cathelicidin antimicrobial peptide (CAMP) and defensin β-4 (DEFB4) genes in normal and transformed cells to combat pathogenic infections. |
In vivo | Ercalcitriol binds to vitamin D receptor (VDR), a nuclear receptor, activates the interaction between VDR and retinol X receptor (RXR) to form VDR/RXR/ cofactor complex, which binds to Vitamin D response elements in the promoter region of target genes to regulate gene transcription[3]. |
Alias | 1α,25-Dihydroxy Vitamin D2 |
Molecular Weight | 428.65 |
Formula | C28H44O3 |
Cas No. | 60133-18-8 |
Storage | store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45.0 mg/mL (105.0 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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