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Ercalcitriol

Catalog No. TQ0216Cas No. 60133-18-8
Alias 1α,25-Dihydroxy Vitamin D2

Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2 that strengthens immunity by regulating cathelicidin antimicrobial peptide (CAMP) and defensin β-4 (DEFB4) genes in normal and transformed cells, combating pathogenic infections.

Ercalcitriol

Ercalcitriol

Purity: 99.02%
Catalog No. TQ0216Alias 1α,25-Dihydroxy Vitamin D2Cas No. 60133-18-8
Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2 that strengthens immunity by regulating cathelicidin antimicrobial peptide (CAMP) and defensin β-4 (DEFB4) genes in normal and transformed cells, combating pathogenic infections.
Pack SizePriceAvailabilityQuantity
1 mg$97In Stock
5 mg$437In Stock
10 mg$648In Stock
25 mg$987In Stock
50 mgInquiryIn Stock
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Purity:99.02%
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Product Introduction

Bioactivity
Description
Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2 that strengthens immunity by regulating cathelicidin antimicrobial peptide (CAMP) and defensin β-4 (DEFB4) genes in normal and transformed cells, combating pathogenic infections.
In vivo
Ercalcitriol binds to vitamin D receptor (VDR), a nuclear receptor, activates the interaction between VDR and retinol X receptor (RXR) to form VDR/RXR/ cofactor complex, which binds to Vitamin D response elements in the promoter region of target genes to regulate gene transcription[3].
Alias1α,25-Dihydroxy Vitamin D2
Chemical Properties
Molecular Weight428.65
FormulaC28H44O3
Cas No.60133-18-8
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45.0 mg/mL (105.0 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3329 mL11.6645 mL23.3291 mL116.6453 mL
5 mM0.4666 mL2.3329 mL4.6658 mL23.3291 mL
10 mM0.2333 mL1.1665 mL2.3329 mL11.6645 mL
20 mM0.1166 mL0.5832 mL1.1665 mL5.8323 mL
50 mM0.0467 mL0.2333 mL0.4666 mL2.3329 mL
100 mM0.0233 mL0.1166 mL0.2333 mL1.1665 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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