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F16 ((E)-4-(3-indolylvinyl)-N-methylpyridinium iodide) inhibits the growth of neu-overexpressing cells and the proliferation of mammary epithelial.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $30 | In Stock | |
10 mg | $47 | In Stock | |
25 mg | $97 | In Stock | |
50 mg | $177 | In Stock | |
100 mg | $258 | In Stock | |
200 mg | $389 | In Stock | |
1 mL x 10 mM (in DMSO) | $52 | In Stock |
Description | F16 ((E)-4-(3-indolylvinyl)-N-methylpyridinium iodide) inhibits the growth of neu-overexpressing cells and the proliferation of mammary epithelial. |
In vitro | F16 arrests the cell cycle and increases apoptosis in F16-sensitive EpH4-A6 cells. F16 (3 μM) influences growth in human and mice cancer cell lines[1]. F16 shows mitochondriotoxic property and triggers apoptosis or necrosis depending on the genetic background of the target carcinoma cell[2]. |
Alias | (E)-4-(3-indolylvinyl)-N-methylpyridinium iodide |
Molecular Weight | 362.21 |
Formula | C16H15IN2 |
Cas No. | 36098-33-6 |
Smiles | [I-].C[n+]1ccc(\C=C\c2c[nH]c3ccccc23)cc1 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 40 mg/mL (82.8 mM) Ethanol: 1 mg/mL (2.76 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
DMSO
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