Shopping Cart

Remove All
Your shopping cart is currently empty

FR901464

Name: FR901464
Brand: TargetMol
SKU: T31866
Price: 328 USD
Availability: InStock
Rating: 5 (10 reviews)

FR901464 (WB 2663B) is potent cytotoxic natural products that share an amine-containing tetrahydropyran ring.

Catalog No. T31866Cas No. 146478-72-0

Select Batch

Purity:98.47%

Resource Download

COA HPLC HNMR

FR901464

Catalog No. T31866Cas No. 146478-72-0

FR901464 (WB 2663B) is potent cytotoxic natural products that share an amine-containing tetrahydropyran ring.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$328	In Stock
5 mg	$788	In Stock
10 mg	$1,120	In Stock
25 mg	$1,660	In Stock
50 mg	$2,230	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "FR901464"

Product Introduction

Bioactivity

Description	FR901464 (WB 2663B) is potent cytotoxic natural products that share an amine-containing tetrahydropyran ring.
In vitro	FR901464 (10-20 ng/ml; 6-24 hours) inhibited the growth of solid tumors, colon cancer, and methoxamine A fibrosarcoma in mice. FR901464 induced characteristic G1 and G2/M phase arrest in the cell cycle and internucleosomal degradation of genomic DNA in M-8 tumor cells by the same principle as SV40 promoter dependent cellular transcription. FR901464 (1-10 ng/ml) induced the transcription of some endogenous genes in M-8 cells, but did not inhibit the transcription of endogenous genes[1].
Alias	FR 901464, FR-901464, WB 2663B

Chemical Properties

Molecular Weight	507.62
Formula	C₂₇H₄₁NO₈
Cas No.	146478-72-0

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 90.0 mg/mL (177.3 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9700 mL	9.8499 mL	19.6998 mL	98.4989 mL
5 mM	0.3940 mL	1.9700 mL	3.9400 mL	19.6998 mL
10 mM	0.1970 mL	0.9850 mL	1.9700 mL	9.8499 mL
20 mM	0.0985 mL	0.4925 mL	0.9850 mL	4.9249 mL
50 mM	0.0394 mL	0.1970 mL	0.3940 mL	1.9700 mL
100 mM	0.0197 mL	0.0985 mL	0.1970 mL	0.9850 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

FR901464