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G108

🥰Excellent
Catalog No. T69663Cas No. 2369750-66-1
Alias G-108, G 108

G108 is an inhibitor of human cGAS and is used in the study of autoimmune diseases associated with human cGAS.

G108

G108

🥰Excellent
Purity: 99.94%
Catalog No. T69663Alias G-108, G 108Cas No. 2369750-66-1
G108 is an inhibitor of human cGAS and is used in the study of autoimmune diseases associated with human cGAS.
Pack SizePriceAvailabilityQuantity
1 mg$490In Stock
5 mg$1,130In Stock
10 mg$1,530In Stock
25 mg$2,270In Stock
50 mg$2,970In Stock
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Purity:99.94%
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Product Introduction

Bioactivity
Description
G108 is an inhibitor of human cGAS and is used in the study of autoimmune diseases associated with human cGAS.
AliasG-108, G 108
Chemical Properties
Molecular Weight365.21
FormulaC16H14Cl2N4O2
Cas No.2369750-66-1
SmilesO=C(N1CC=2C=3C(=CC(Cl)=C(Cl)C3NC2CC1)C=4C=NNC4)CO
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 120 mg/mL (210.87 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM2.7382 mL13.6908 mL27.3815 mL136.9075 mL
5 mM0.5476 mL2.7382 mL5.4763 mL27.3815 mL
10 mM0.2738 mL1.3691 mL2.7382 mL13.6908 mL
20 mM0.1369 mL0.6845 mL1.3691 mL6.8454 mL
50 mM0.0548 mL0.2738 mL0.5476 mL2.7382 mL
100 mM0.0274 mL0.1369 mL0.2738 mL1.3691 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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