Shopping Cart
- Remove All
Your shopping cart is currently empty
IRAK4-IN-4
🥰Excellent
Catalog No. T11673Cas No. 1850276-58-2
IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.
IRAK4-IN-4
🥰Excellent
Purity: 99.52%
Catalog No. T11673Cas No. 1850276-58-2
IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $58 | In Stock | |
| 5 mg | $148 | In Stock | |
| 10 mg | $223 | In Stock | |
| 25 mg | $397 | In Stock | |
| 50 mg | $596 | In Stock | |
| 100 mg | $858 | In Stock | |
| 200 mg | $1,150 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $163 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "IRAK4-IN-4"
ANTHRAQUINONE-2-CARBOXYLIC ACID
Cited
T7035117-78-2
Anthraquinone-2-carboxylic acid acts as a potent anti-inflammatory and antinociceptive component in vivo, thus contributing to the immune regulatory role of fruits and herbs.
- $34
Size
QTY
CitedGinsenoside Rb1
Gypenoside III, Gypenoside Ⅲ
T282241753-43-9
Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.
- $39
Size
QTY
Thalidomide 4-fluoride
E3 ligase Ligand 4
T7755835616-60-9
Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.
- $29
Size
QTY
AS-2444697
T42991287665-60-4
AS-2444697 is an inhibitor of IRAK-4 (C50 = 21 nM). AS-2444697 exhibits renoprotective effects through anti-inflammatory action. AS-2444697 potently inhibits human and rat IRAK-4 activity.
- $30
Size
QTY
GLPG2534
GLPG-2534
T751132095615-97-5In house
GLPG2534 is an orally active, selective and potent IRAK4 inhibitor with anti-inflammatory activity. GLPG2534 inhibits human and mouse IRAK4 and could be used to study psoriasis and atopic dermatitis.
- $113
Size
QTY
IRAK inhibitor 2
IRAK-IN-2
T7368928333-30-6In house
IRAK inhibitor 2 (IRAK-IN-2) is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK-4) for the study of inflammation-related diseases.
- $78
Size
QTY
Zimlovisertib
PF-06650833, PF06650833
TQ01671817626-54-2
Zimlovisertib (PF-06650833) is an effective, selective and orally active inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4) (IC50s: 0.2 and 2.4 nM in the cell and PBMC assay).
- $39
Size
QTY
IRAK-1-4 Inhibitor I
IRAK-1/4 Inhibitor I, IRAK-1/4 Inhibitor
T2457509093-47-4
IRAK-1-4 Inhibitor I is a dual inhibitor targeting IRAK1 and IRAK4.
- $37
Size
QTY
IRAK4-IN-1
T41401820787-94-7
IRAK4-IN-1 is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.
- $64
Size
QTY
IRAK inhibitor 1
T50941042224-63-4
IRAK inhibitor 1 is an effective IRAK-4 inhibitor (IC50: 216 nM), is poorly active against JNK-1 (IC50: 3.801 μM) and JNK-2 (IC50>10 μM).
- $87
Size
QTY
Zabedosertib
BAY 1834845
T370761931994-81-8In house
Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential. Zabedosertib protects against acute respiratory distress syndrome, a new study suggests.
- $36
Size
QTY
JH-X-119-01
T92032227368-54-7
JH-X-119-01 is a highly potent and selective covalent inhibitor of IRAK-1 (Interleukin-1 Receptor-Associated Kinase 1).
- $60
Size
QTY
Select Batch
Purity:99.52%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM. |
| Targets&IC50 | cGAS:2.1 nM (IC50), IRAK4:2.8 nM (IC50) |
| Molecular Weight | 340.37 |
| Formula | C22H16N2O2 |
| Cas No. | 1850276-58-2 |
| Smiles | Cc1ccn2c(C(=O)C(=O)c3ccccc3)c(nc2c1)-c1ccccc1 |
| Relative Density. | 1.20 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 24 mg/mL (70.51 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
| |||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy IRAK4-IN-4 | purchase IRAK4-IN-4 | IRAK4-IN-4 cost | order IRAK4-IN-4 | IRAK4-IN-4 chemical structure | IRAK4-IN-4 formula | IRAK4-IN-4 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.