Shopping Cart

Remove All

Your shopping cart is currently empty

GATA4-NKX2-5-IN-1

Select Batch

Purity:99.00%

Resource Download

COA HNMR HPLC

GATA4-NKX2-5-IN-1

Catalog No. T11368Cas No. 544681-96-1

GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist-induced cardiac gene expression.GATA4-NKX2-5-IN-1 dose-dependently inhibits the GATA4–NKX2-5 transcriptional synergy with an IC50 of 3 μM.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$93	In Stock
5 mg	$228	In Stock
10 mg	$313	In Stock
25 mg	$496	In Stock
50 mg	$668	In Stock
100 mg	$892	In Stock
1 mL x 10 mM (in DMSO)	$253	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "GATA4-NKX2-5-IN-1"

Product Introduction

Bioactivity

Description	GATA4-NKX2-5-IN-1 exhibits no activity on the protein kinases involved in the regulation of GATA4 phosphorylation, and it modulates the hypertrophic agonist-induced cardiac gene expression.GATA4-NKX2-5-IN-1 dose-dependently inhibits the GATA4–NKX2-5 tran
Targets&IC50	GATA4–NKX2-5:3 μM

Chemical Properties

Molecular Weight	349.43
Formula	C21H23N3O2
Cas No.	544681-96-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 65 mg/ml (186.02 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8618 mL	14.3090 mL	28.6180 mL	143.0902 mL
5 mM	0.5724 mL	2.8618 mL	5.7236 mL	28.6180 mL
10 mM	0.2862 mL	1.4309 mL	2.8618 mL	14.3090 mL
20 mM	0.1431 mL	0.7155 mL	1.4309 mL	7.1545 mL
50 mM	0.0572 mL	0.2862 mL	0.5724 mL	2.8618 mL
100 mM	0.0286 mL	0.1431 mL	0.2862 mL	1.4309 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

GATA4 NKX2 5 IN 1inhibitGATA-4-NKX2-5-IN-1InhibitorGATA4-NKX2-5-IN-1GATA4NKX25IN1