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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $33 | In Stock | |
2 mg | $46 | In Stock | |
5 mg | $73 | In Stock | |
10 mg | $106 | In Stock | |
25 mg | $178 | In Stock | |
50 mg | $271 | In Stock | |
100 mg | $393 | In Stock | |
500 mg | $816 | In Stock | |
1 mL x 10 mM (in DMSO) | $85 | In Stock |
Description | GBR 12783 dihydrochloride (GBR12783 2HCl) is a specific, potent and selective dopamine uptake inhibitor. GBR 12783 dihydrochloride inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively.GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats. |
In vivo | GBR 12783 (10 mg/kg; intraperitoneal injection; for 100 minutes; male Sprague-Dawley rats) treatment reinforces specifically dopamine transmission only at synapses instantaneously active, increases hippocampal ACh release and improves memory performance in a passive avoidance task[1]. |
Alias | GBR12783 2HCl |
Molecular Weight | 485.49 |
Formula | C28H34Cl2N2O |
Cas No. | 67469-75-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45 mg/mL (92.69 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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