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Gcase activator 2
🥰Excellent
Catalog No. T86495Cas No. 2759897-35-1
Gcase activator 2 is a β-glucocerebrosidase activator that induces dimerization of GCase at the endoplasmic reticulum (ER) and lysosomal pHs, increases lysosomal substrate metabolism, and has therapeutic potential for the treatment of Parkinson's and Gosheimer's diseases.
Gcase activator 2
🥰Excellent
Purity: 99.79%
Catalog No. T86495Cas No. 2759897-35-1
Gcase activator 2 is a β-glucocerebrosidase activator that induces dimerization of GCase at the endoplasmic reticulum (ER) and lysosomal pHs, increases lysosomal substrate metabolism, and has therapeutic potential for the treatment of Parkinson's and Gosheimer's diseases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 116 € | In Stock | |
| 5 mg | 281 € | In Stock | |
| 10 mg | 493 € | In Stock | |
| 25 mg | 790 € | In Stock | |
| 50 mg | 1.064 € | In Stock | |
| 100 mg | 1.415 € | In Stock | |
| 200 mg | 1.881 € | In Stock | |
| 1 mL x 10 mM (in DMSO) | 316 € | In Stock |
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Purity:99.79%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Gcase activator 2 is a β-glucocerebrosidase activator that induces dimerization of GCase at the endoplasmic reticulum (ER) and lysosomal pHs, increases lysosomal substrate metabolism, and has therapeutic potential for the treatment of Parkinson's and Gosheimer's diseases. |
| In vitro | Gcase activator 2 exhibits a low metabolic clearance rate in both humans and mice, with CL values of 10 and 12 μL/min/mg, respectively [1]. |
| Molecular Weight | 364.44 |
| Formula | C21H24N4O2 |
| Cas No. | 2759897-35-1 |
| Smiles | O=C(N1CCC(C2=CC=3N=C(C=NC3N2C)C4=CC=C(OC)C=C4)CC1)C |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (219.51 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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