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GGFG-PAB-MMAE
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Catalog No. T201132Cas No. 3049886-19-0
GGFG-PAB-MMAE (Comp 58054-1) is a drug-linker conjugate for ADC that comprises an ADC linker (GGFG-PAB) and the potent tubulin polymerization inhibitor, MMAE. This formulation combines the targeted delivery mechanism inherent in ADC technology with the effective inhibitory action of MMAE against tubulin polymerization.
GGFG-PAB-MMAE
😃Good
Catalog No. T201132Cas No. 3049886-19-0
GGFG-PAB-MMAE (Comp 58054-1) is a drug-linker conjugate for ADC that comprises an ADC linker (GGFG-PAB) and the potent tubulin polymerization inhibitor, MMAE. This formulation combines the targeted delivery mechanism inherent in ADC technology with the effective inhibitory action of MMAE against tubulin polymerization.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | GGFG-PAB-MMAE (Comp 58054-1) is a drug-linker conjugate for ADC that comprises an ADC linker (GGFG-PAB) and the potent tubulin polymerization inhibitor, MMAE. This formulation combines the targeted delivery mechanism inherent in ADC technology with the effective inhibitory action of MMAE against tubulin polymerization. |
| Molecular Weight | 1185.45 |
| Formula | C62H92N10O13 |
| Cas No. | 3049886-19-0 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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