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GLP-1R Agonist DMB
🥰Excellent
Catalog No. T36579Cas No. 281209-71-0
GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor).
GLP-1R Agonist DMB
🥰Excellent
Purity: 99.52%
Catalog No. T36579Cas No. 281209-71-0
GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 44 € | In Stock | |
| 5 mg | 135 € | In Stock | |
| 10 mg | 236 € | In Stock | |
| 25 mg | 403 € | In Stock | |
| 50 mg | Inquiry | In Stock |
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Purity:99.52%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor). |
| In vitro | GLP-1R Agonist DMB inhibits forskolin-induced cAMP accumulation in BHK cells expressing the recombinant human receptor with an EC50 value of 101 nM. GLP-1R Agonist DMB (100 and 1,000 nM) increases insulin levels induced by D-(+)-glucose in pancreatic islets isolated from wild-type, but not Glp1r knockout, mice[1]. |
| In vivo | GLP-1R Agonist DMB reduces fasting plasma glucose levels in mice when administered at a dose of 5 μmol/kg[1]. |
| Molecular Weight | 348.25 |
| Formula | C13H15Cl2N3O2S |
| Cas No. | 281209-71-0 |
| Smiles | CC(C)(C)Nc1nc2cc(Cl)c(Cl)cc2nc1S(C)(=O)=O |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 9 mg/mL (25.8 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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