Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 47.00 | |
5 mg | In stock | $ 143.00 | |
10 mg | In stock | $ 249.00 | |
25 mg | In stock | $ 425.00 | |
50 mg | In stock | Inquiry |
Description | GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor). |
In vitro | GLP-1R Agonist DMB inhibits forskolin-induced cAMP accumulation in BHK cells expressing the recombinant human receptor with an EC50 value of 101 nM. GLP-1R Agonist DMB (100 and 1,000 nM) increases insulin levels induced by D-(+)-glucose in pancreatic islets isolated from wild-type, but not Glp1r knockout, mice[1]. |
In vivo | GLP-1R Agonist DMB reduces fasting plasma glucose levels in mice when administered at a dose of 5 μmol/kg[1]. |
Molecular Weight | 348.25 |
Formula | C13H15Cl2N3O2S |
CAS No. | 281209-71-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 9mg/mL (25.8mM)
You can also refer to dose conversion for different animals. More
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GLP-1R Agonist DMB 281209-71-0 GPCR/G Protein Glucagon Receptor GLP1R Agonist DMB GLP 1R Agonist DMB inhibitor inhibit