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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $64 | In Stock | |
10 mg | $113 | In Stock | |
25 mg | $228 | In Stock | |
50 mg | $413 | In Stock | |
100 mg | $618 | In Stock | |
500 mg | $1,330 | In Stock | |
1 mL x 10 mM (in DMSO) | $74 | In Stock |
Description | GT 949 is a selective excitatory positive allosteric modulator of amino acid transporter-2 (EAAT2) with an EC50 of 0.26 nM. |
Targets&IC50 | EAAT2:(EC50)0.26±0.03 nM |
In vitro | GT 949 displays selectivity to EAAT2 and has no effect on glutamate activity mediated by EAAT1 or EAAT3. GT 949 improves glutamate transport (EC50 = 0.26 nM) and increases glutamate transport in a non-competitive manner with an increase in Vmax of about 47% in EAAT2-transfected cells[1]. |
Molecular Weight | 527.66 |
Formula | C30H37N7O2 |
Cas No. | 460330-27-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/mL (104.23 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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