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HKB99

HKB99
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HKB99

Catalog No. T22343Cas No. 2414908-90-8
HKB99 is a mutant inhibitor of phosphoglycerate mutase 1 (PGAM1), which inhibits the growth and metastasis of non-small cell lung cancer.HKB99 acts synergistically with EGFR inhibitors and assists in the killing of tumors by EGFR inhibitors.HKB99 promotes oxidative stress, which induces alterations in a variety of signaling pathways.HKB99 can be used in the study of metabolism-related diseases.HKB99 can be used in the study of metabolism-related diseases.HKB99 can be used in the study of metabolism-related diseases.
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1 mg$257In Stock
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Product Introduction

Bioactivity
Description
HKB99 is a mutant inhibitor of phosphoglycerate mutase 1 (PGAM1), which inhibits the growth and metastasis of non-small cell lung cancer.HKB99 acts synergistically with EGFR inhibitors and assists in the killing of tumors by EGFR inhibitors.HKB99 promotes oxidative stress, which induces alterations in a variety of signaling pathways.HKB99 can be used in the study of metabolism-related diseases.HKB99 can be used in the study of metabolism-related diseases.HKB99 can be used in the study of metabolism-related diseases.
Chemical Properties
Molecular Weight450.46
FormulaC23H18N2O6S
Cas No.2414908-90-8
Storage & Solubility Information
Storagestore at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 100 mg/mL (222.00 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2200 mL11.0998 mL22.1995 mL110.9976 mL
5 mM0.4440 mL2.2200 mL4.4399 mL22.1995 mL
10 mM0.2220 mL1.1100 mL2.2200 mL11.0998 mL
20 mM0.1110 mL0.5550 mL1.1100 mL5.5499 mL
50 mM0.0444 mL0.2220 mL0.4440 mL2.2200 mL
100 mM0.0222 mL0.1110 mL0.2220 mL1.1100 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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