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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $317 | In Stock |
Description | HPN-01 (IKK inhibitor XII) is a selective IKK inhibitor that inhibits IKK-α, IKK-β, and IKK-ε. HPN-01 reduces the severity of the disease, attenuates the immune imbalance, and prolongs the lifespan of mice in a model of autoimmune encephalomyelitis, and can be used to study immune disorders. |
In vitro | HPN-01 could inhibit the expression of SREBP-1 and SREBP-2 in human primary hepatocytes, and the IC50 values were 1.71 and 3.43, respectively. It is commonly used in the study of nonalcoholic fatty liver disease (NAFLD)[1]. |
Alias | HPN 01, HPN01 |
Molecular Weight | 401.87 |
Formula | C19H16ClN3O3S |
Cas No. | 928655-63-4 |
Storage | store at low temperature|Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (199.07 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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