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I-BET762 carboxylic acid
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Catalog No. T13086Cas No. 1300019-38-8
Alias PROTAC BRD4-binding moiety 2, Molibresib carboxylic acid, GSK525762A carboxylic acid
I-BET762 carboxylic acid is an inhibitor of BRD4(pIC50 of 5.1).
I-BET762 carboxylic acid
😃Good
Catalog No. T13086Alias PROTAC BRD4-binding moiety 2, Molibresib carboxylic acid, GSK525762A carboxylic acidCas No. 1300019-38-8
I-BET762 carboxylic acid is an inhibitor of BRD4(pIC50 of 5.1).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $48 | 5 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | I-BET762 carboxylic acid is an inhibitor of BRD4(pIC50 of 5.1). |
| Targets&IC50 | BRD4:5.1(pIC50) |
| In vitro | peripheral blood mononuclear cells (PBMC) inhibited by I-BET762 carboxylic acid(pIC50 of <4). |
| Alias | PROTAC BRD4-binding moiety 2, Molibresib carboxylic acid, GSK525762A carboxylic acid |
| Molecular Weight | 396.83 |
| Formula | C20H17ClN4O3 |
| Cas No. | 1300019-38-8 |
| Relative Density. | 1.44 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
| Solubility Information | DMSO: 7.14 mg/mL (17.99 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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