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Idramantone

🥰Excellent
Catalog No. T1588Cas No. 20098-14-0
Alias Kemantane, 5-Hydroxy-2-adamantanone

Idramantone (Kemantane) is an immune agonist.

Idramantone

Idramantone

🥰Excellent
Purity: 99.25%
Catalog No. T1588Alias Kemantane, 5-Hydroxy-2-adamantanoneCas No. 20098-14-0
Idramantone (Kemantane) is an immune agonist.
Pack SizePriceAvailabilityQuantity
200 mg$31 In Stock
500 mg$48 In Stock
1 g$70 In Stock
5 g$168 In Stock
1 mL x 10 mM (in DMSO)$39 In Stock
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Purity:99.25%
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Product Introduction

Bioactivity
Description
Idramantone (Kemantane) is an immune agonist.
Kinase Assay
Assays with human placental aromatase: Microsomes are prepared from human placenta and stored at -80℃. The rate of aromatization is determined by measuring the tritiated water released from [1β-3H]A. The assay is carried out in a final volume of 1 mL, in 10 mM phosphate buffer, pH 7.5, containing 100 mM KCl, 1 mM EDTA, 1 mM dithiothreitol, 100 μM NADPH, the enzyme preparation and the appropriate concentrations of Exemestane (in duplicate) and the substrate. After a 10 min incubation at 37 ℃, the assay is terminated by the addition of 4 mL cold chloroform. The acqueous phase is treated with a charcoal suspension, the supernatant is removed and counted for radioactivity by liquid scintillation in Rialuma. For the determination of the IC50 values, various concentrations of Exemestane are incubated with 20 μg of microsomal protein, in the presence of a fixed amount (50 nM) of [3H]A.
AliasKemantane, 5-Hydroxy-2-adamantanone
Chemical Properties
Molecular Weight166.22
FormulaC10H14O2
Cas No.20098-14-0
SmilesOC12CC3CC(C1)C(=O)C(C3)C2
Relative Density.1.301g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 31 mg/mL (186.5 mM), Sonication is recommended.
H2O: 30 mg/mL (180.48 mM), Sonication is recommended.
DMSO: 45 mg/mL (270.73 mM), Sonication is recommended.
Solution Preparation Table
H2O/Ethanol/DMSO
1mg5mg10mg50mg
1 mM6.0161 mL30.0806 mL60.1612 mL300.8062 mL
5 mM1.2032 mL6.0161 mL12.0322 mL60.1612 mL
10 mM0.6016 mL3.0081 mL6.0161 mL30.0806 mL
20 mM0.3008 mL1.5040 mL3.0081 mL15.0403 mL
50 mM0.1203 mL0.6016 mL1.2032 mL6.0161 mL
100 mM0.0602 mL0.3008 mL0.6016 mL3.0081 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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