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Idramantone (Kemantane) is an immune agonist.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
200 mg | $31 | In Stock | |
500 mg | $48 | In Stock | |
1 g | $70 | In Stock | |
5 g | $168 | In Stock | |
1 mL x 10 mM (in DMSO) | $39 | In Stock |
Description | Idramantone (Kemantane) is an immune agonist. |
Kinase Assay | Assays with human placental aromatase: Microsomes are prepared from human placenta and stored at -80℃. The rate of aromatization is determined by measuring the tritiated water released from [1β-3H]A. The assay is carried out in a final volume of 1 mL, in 10 mM phosphate buffer, pH 7.5, containing 100 mM KCl, 1 mM EDTA, 1 mM dithiothreitol, 100 μM NADPH, the enzyme preparation and the appropriate concentrations of Exemestane (in duplicate) and the substrate. After a 10 min incubation at 37 ℃, the assay is terminated by the addition of 4 mL cold chloroform. The acqueous phase is treated with a charcoal suspension, the supernatant is removed and counted for radioactivity by liquid scintillation in Rialuma. For the determination of the IC50 values, various concentrations of Exemestane are incubated with 20 μg of microsomal protein, in the presence of a fixed amount (50 nM) of [3H]A. |
Alias | Kemantane, 5-Hydroxy-2-adamantanone |
Molecular Weight | 166.22 |
Formula | C10H14O2 |
Cas No. | 20098-14-0 |
Smiles | OC12CC3CC(C1)C(=O)C(C3)C2 |
Relative Density. | 1.301g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | Ethanol: 31 mg/mL (186.5 mM), Sonication is recommended. H2O: 30 mg/mL (180.48 mM), Sonication is recommended. DMSO: 45 mg/mL (270.73 mM), Sonication is recommended. ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O/Ethanol/DMSO
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