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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $117 | In Stock | |
5 mg | $289 | In Stock | |
10 mg | $455 | In Stock | |
25 mg | $778 | In Stock | |
50 mg | $1,090 | In Stock | |
100 mg | $1,530 | In Stock | |
1 mL x 10 mM (in DMSO) | $318 | In Stock |
Description | IP7e (isoxazolo-pyridinone 7e) is a Nurr1 activator with an EC50 value of 3.9 nM. |
Targets&IC50 | Nurr1:3.9 nM(EC50) |
In vivo | IP7e(10 mg/kg) attenuates inflammation and neurodegeneration in spinal cords of EAE mice by an NF-kB pathway-dependent process. IP7e preventive treatment reduces the incidence and the severity of an MS murine model, i.e. experimental autoimmune encephalomyelitis (EAE)[1]. |
Alias | IP 7e, IP-7e, isoxazolo-pyridinone 7e |
Molecular Weight | 390.43 |
Formula | C23H22N2O4 |
Cas No. | 500164-74-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 95 mg/mL (243.32 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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