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Search Results for " orally "

Targets

3333

Compounds

81

Natural Products

1

Libraries

Cat No. Product Name Synonyms Targets
T8348 Phentolamine Adrenergic Receptor
Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist
T8345 Carbutamide Others
Carbutamide is a sulfonylurea antidiabetic agent with hypoglycemic activity.
T35862 Cucurbit[8]uril Others
Cucurbit[8]uril is a highly effective and safe supramolecular compound that promotes protein heterodimerization. It selectively induces the heterodimerization of methylviologen and naphthalene functionalized proteins, de...
T9565 OSBPL7-IN-1 Others
OSBPL7-IN-1 is an orally active inhibitor of oxysterol binding protein like 7 (OSBPL7). OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression[1].
T8580 Bupranolol Adrenergic Receptor
Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.
T9692 Paltusotine Somatostatin
Paltusotine is a nonpeptide, small molecule somatostatin type 2 (SST2) receptor agonist with high oral bioavailability. Paltusotine maintains GH and IGF-1 levels in acromegaly patients
T1292 Tiapride hydrochloride Dopamine Receptor
Tiapride is a selective blocker of D2/3 dopamine receptors in the brain. It is used in the therapy of various psychiatric and neurological disorders containing dyskinesia, negative symptoms of psychosis, alcohol withdraw...
T9732 VY-3-135 Fatty Acid Synthase
VY-3-135 is a metastasis inhibitor and an acetyl-CoA synthetase 2 (ACSS2) modulator.
T8734 Choline Others
Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins
T15500 HPi1 Others , Antibacterial
HPi1 is a selective and orally active antimicrobial against Helicobacter pylori (IC50: 0.24 μM and a MIC of 0.08-0.16 μg/mL). HPi1 is inactive against other Xaliproden, including the gut commensals, Lactobacillus reuteri...
T34896 Tofisopam Emandaxin,Grandaxin Others
Tofisopam (Grandaxin) is a 2,3-benzodiazepine derivative with anti-anxiety property.
T3306 PF-04418948 PF 04418948,PF04418948 Prostaglandin Receptor
PF-04418948 is a potent EP2 receptor antagonist (IC50 = 16 nM for human EP2 receptors). Displays over 2000-fold selectivity for EP2 receptors over EP1, EP3, EP4, DP1 amd CRTH2 receptors; exhibits <30% binding at a divers...
T16115 MLi-2 LRRK2
MLi-2 is a structurally novel, highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro (IC50 = 0.76 nM), a ce...
T9214 ELOVL6-IN-1 Others
ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities, with an IC50 value of 0.350 μM. ELOVL6-IN-1 inhibits ELOVL6 in a noncompetitive manner...
T9683 VX-150 Sodium Channel
VX-150 is a highly selective NaV1.8 inhibitor relative to the other sodium channel subtypes (>400-fold).
T39695 ARD-2128 Androgen Receptor
ARD-2128 is a highly potent, orally bioavailable PROTAC degrader of androgen receptor (AR). ARD-2128 effectively reduces AR protein, suppresses AR-regulated genes in tumor tissues, and inhibits growth of tumor without si...
T9215 ELOVL6-IN-2 Others
ELOVL6-IN-2 is a orally active and selective ELOVL6 inhibitor.
T6710 Troxipide Aplace Others
Troxipide (Aplace), a new-type systemic non-antisecretory gastric cytoprotective agent, which is mucus-secreting, anti-ulcer, and anti-inflammatory properties irrespective of pH of stomach or duodenum.
T2013 Ponalrestat Reductase
Ponalrestat is an aldose reductase inhibitor.
T9805 BAY 2666605 PDE
BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 has anticancer effects.
T9164 BMS-986242 BMS986242 IDO , Indoleamine 2,3-Dioxygenase (IDO)
BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.
T21740 RD162 Androgen Receptor
RD162 is a non-steroidal antiandrogen (NSAA) specifically binding to the androgen receptor (AR).
T3713 BAY-876 transporter
BAY-876 is an orally active and selective inhibitor of glucose transporter 1 (GLUT1, IC50= 2 nM). BAY-876 exhibits >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 also inhibits glycolytic metabol...
T9590 T-1095 SGLT , transporter
T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).
T38776 LP-922056 Wnt/beta-catenin
LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.
T2436 GSK2801 Apoptosis , Epigenetic Reader Domain
GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.
T10096L Voruciclib CDK
Voruciclib is an orally active and selective CDK inhibitor (Ki: 0.626 nM-9.1 nM). Voruciclib represses the expression of MCL-1 in multiple models of diffuse large B-cell lymphoma. Voruciclib effectively blocks CDK9, the ...
T9977 SGK1-IN-4 SGK
SGK1-IN-4 is a selective inhibitor of SGK1 and can be used in studies about osteoarthritis.
T11339 Furegrelate sodium U-63557A PPAR
Furegrelate sodium (U-63557A) is a selective thromboxane synthase inhibitor with oral activity. Furegrelate sodium(U-63557A) inhibits thromboxane A2 (TXA2) synthase in human platelet microsomes with an IC50 of 15 nM.
T2629 UNC2881 TAM Receptor
UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively.
T13186 TL02-59 Apoptosis , Src , Hck
TL02-59 is a selective inhibitor of Fgr in Src-family kinase (IC50 = 0.03 nM). TL02-59 inhibits Lyn and Hck with IC50s of 0.1 nM and 160 nM, respectively. TL02-59 potently suppresses acute myelogenous leukemia cell growt...
T40548 NH-3 Thyroid hormone receptor(THR)
NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the selective thyromi-metic GC-1, NH-3 effectively inhibits the...
T12266 Ilginatinib NS-018 Tyrosine Kinases , JAK
Ilginatinib (NS-018) is a highly active and orally bioavailable inhibitor of JAK2.
T8432 ASP4132 AMPK
ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity.
T12401 Pemigatinib INCB054828 FGFR
Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively).
T7686 Ramiprilat RAAS
Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T5491 GSK3179106 c-RET
GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nM
T25492 Hepln-13 Hepln 13,Hepln13 c-Met/HGFR
Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis.
T15656 KGA-2727 SGLT
KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA...
T5347 CXD101 CXD-101 HDAC
CXD101 is a novel class I-selective HDACi (HDAC1 (IC50 : 63nM), HDAC2 (IC50 :570nM), HDAC3 (IC50 :550nM)). CXD101(CXD-101) has no activity against HDAC class II
T12979 BI-3406 p38 MAPK , MAPK , Ras
BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 : 6 nM),with anticancer activity.
T8581 Flecainide hydrochloride Others
Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.
T10525 SCD1 inhibitor-4 Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.
T8322 BL-918 Autophagy
BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM.
T4061 LY2334737 Nucleoside Antimetabolite/Analog , Others , Virus Protease
LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.
T11399 Giredestrant GDC-9545 Estrogen Receptor/ERR , Estrogen/progestogen Receptor
Giredestrant (GDC-9545) potently competes with estradiol for binding and induces a conformational change within the ER ligand binding domain. Giredestrant has anti-tumor activity. Giredestrant, a non-steroidal ER ligand,...
T21712 BAY 41-8543 Others , Guanylate cyclase
BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).
T9043 AS1810722 P450 , STAT
AS1810722 is an orally active and potent STAT6 inhibitor(IC50 :1.9 nM). AS1810722 shows a good profile of CYP3A4 inhibition. AS1810722, a derivative of fused bicyclic pyrimidine, has the potential for allergic diseases s...
T9575 MRTX9768 Histone Methyltransferase
MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors.
T36670 JNJ-67856633 MALT
JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease . JNJ-67856633 lead to tumor stasis in some cases.

Compounds

Phentolamine
T8348
Synonym:
Target: Adrenergic Receptor
Carbutamide
T8345
Synonym:
Target: Others
Cucurbit[8]uril
T35862
Synonym:
Target: Others
OSBPL7-IN-1
T9565
Synonym:
Target: Others
Bupranolol
T8580
Synonym:
Target: Adrenergic Receptor
Paltusotine
T9692
Synonym:
Target: Somatostatin
Tiapride hydrochloride
T1292
Synonym:
Target: Dopamine Receptor
VY-3-135
T9732
Synonym:
Target: Fatty Acid Synthase
Choline
T8734
Synonym:
Target: Others
HPi1
T15500
Synonym:
Target: Others, Antibacterial
Tofisopam
T34896
Synonym: Emandaxin,Grandaxin
Target: Others
PF-04418948
T3306
Synonym: PF 04418948,PF04418948
Target: Prostaglandin Receptor
MLi-2
T16115
Synonym:
Target: LRRK2
ELOVL6-IN-1
T9214
Synonym:
Target: Others
VX-150
T9683
Synonym:
Target: Sodium Channel
ARD-2128
T39695
Synonym:
Target: Androgen Receptor
ELOVL6-IN-2
T9215
Synonym:
Target: Others
Troxipide
T6710
Synonym: Aplace
Target: Others
Ponalrestat
T2013
Synonym:
Target: Reductase
BAY 2666605
T9805
Synonym:
Target: PDE
BMS-986242
T9164
Synonym: BMS986242
Target: IDO, Indoleamine 2,3-Dioxygenase (IDO)
RD162
T21740
Synonym:
Target: Androgen Receptor
BAY-876
T3713
Synonym:
Target: transporter
T-1095
T9590
Synonym:
Target: SGLT, transporter
LP-922056
T38776
Synonym:
Target: Wnt/beta-catenin
GSK2801
T2436
Synonym:
Target: Apoptosis, Epigenetic Reader Domain
Voruciclib
T10096L
Synonym:
Target: CDK
SGK1-IN-4
T9977
Synonym:
Target: SGK
Furegrelate sodium
T11339
Synonym: U-63557A
Target: PPAR
UNC2881
T2629
Synonym:
Target: TAM Receptor
TL02-59
T13186
Synonym:
Target: Apoptosis, Src, Hck
NH-3
T40548
Synonym:
Target: Thyroid hormone receptor(THR)
Ilginatinib
T12266
Synonym: NS-018
Target: Tyrosine Kinases, JAK
ASP4132
T8432
Synonym:
Target: AMPK
Pemigatinib
T12401
Synonym: INCB054828
Target: FGFR
Ramiprilat
T7686
Synonym:
Target: RAAS
GSK3179106
T5491
Synonym:
Target: c-RET
Hepln-13
T25492
Synonym: Hepln 13,Hepln13
Target: c-Met/HGFR
KGA-2727
T15656
Synonym:
Target: SGLT
CXD101
T5347
Synonym: CXD-101
Target: HDAC
BI-3406
T12979
Synonym:
Target: p38 MAPK, MAPK, Ras
Flecainide hydrochloride
T8581
Synonym:
Target: Others
SCD1 inhibitor-4
T10525
Synonym:
Target: Dehydrogenase, Stearoyl-CoA Desaturase (SCD)
BL-918
T8322
Synonym:
Target: Autophagy
LY2334737
T4061
Synonym:
Target: Nucleoside Antimetabolite/Analog, Others, Virus Protease
Giredestrant
T11399
Synonym: GDC-9545
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor
BAY 41-8543
T21712
Synonym:
Target: Others, Guanylate cyclase
AS1810722
T9043
Synonym:
Target: P450, STAT
MRTX9768
T9575
Synonym:
Target: Histone Methyltransferase
JNJ-67856633
T36670
Synonym:
Target: MALT
1 2 3 4 5 ... 67
Cat No. Product Name Synonyms Targets
TN2081 Maohuoside A MAPK
Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.
T13795 Nicotinamide riboside Sirtuin
Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.
T3858 Macranthoidin A Others
Macranthoidin A has anti-inflammation activity.
T40615 N,N'-Dimethylthiourea DMTU Antioxidant
N,N'-Dimethylthiourea (DMTU) (DMTU), isolated from Allii Sativi Bulbus, is an orally active scavenger of hydroxyl radical ( OH) and blocks OH production by activated neutrophils in vitro. N,N'-Dimethylthiourea protects a...
T4S1114 Dryocrassin ABBA Dryocrassin Influenza Virus , Antibacterial
Dryocrassin ABBA (Dryocrassin) is a flavonoid natural product derived from Dryopteris crassirhizoma, with antiviral and antibacterial activities.
T5S1895 Norisoboldine Laurelliptine,(+)-Laurelliptine MAPK , Adenosine Receptor
1. Norisoboldine ((+)-Laurelliptine) might be a potential therapeutic agent for rheumatoid arthritis, and it functions through protecting joint destruction as well as regulating the abnormal immune responses. 2. Norisobo...
TN2423 Safranal Antioxidant
Safranal is the special volatile aroma compound of saffron
T1560 Prednisolone Predonine,Hydroretrocortine,Metacortandralone Glucocorticoid Receptor , Endogenous Metabolite
Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
T0848 L-DOPA Levodopa,3,4-Dihydroxyphenylalanine Dopamine Receptor , Endogenous Metabolite
L-DOPA (Levodopa) is an amino acid precursor of dopamine with antiparkinsonian properties. Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier. When in the brai...
T5784 Topotecan NSC 609669,SKF 104864A Topoisomerase , Autophagy
Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.
T1611 Isotretinoin 13-cis-Retinoic acid Retinoid Receptor , Endogenous Metabolite , Autophagy
Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturall...
T6368 Abscisic Acid Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin) Others , Proton pump , Endogenous Metabolite
Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth.
T6220 Nicotinamide riboside chloride Sirtuin , Endogenous Metabolite
Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+.
T1326 Gentamicin sulfate SCH9724,Gentamycin sulfate,NSC-82261 ribosome , DHFR , Antibacterial , Antibiotic
Gentamicin sulfate (SCH9724) is a wide-spectrum, aminoglycoside antibiotic used to inhibit protein synthesis in sensitive organisms.
T0974 Novobiocin Sodium Albamycinsodium,Cathomycin,Albamycin Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy
Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim...
T5283 NADH disodium salt Disodium NADH,NADH, disodium salt hydrate Others , Endogenous Metabolite
NADH disodium salt (Disodium NADH) hydrate is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process, NADH disodium salt hydrate becomes oxid...
T7727 Se-Methylselenocysteine Se MSC,SeMCys,MSeC,Se-MSC,SeMSC BCL , IAP , Caspase
Se-Methylselenocysteine (Se-MSC) is a potent chemopreventive agent in many test systems and has been shown to inhibit tumor promotion and induce apoptosis.
T6194 Fidaxomicin Tiacumicin B,OPT-80,Clostomicin B1,PAR-101 Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic
Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults. Fidaxomicin has minimal systemic absorption and has not been linked to serum enzyme el...
T2719 Succinic acid Asuccin,Amber acid,1,2-Ethanedicarboxylic acid,Wormwood acid,Butanedioic acid,1,4-Butandioic Acid Endogenous Metabolite
Succinic acid (1,2-Ethanedicarboxylic acid) is a water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is al...
T3417 Amentoflavone Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin Apoptosis , P450 , Phospholipase , Reactive Oxygen Species , Opioid Receptor , COX , Antibacterial , RSV , Antifungal
Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhib...
T2755 Rhoifolin Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy
Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
T6460 Cysteamine hydrochloride 2-Mercaptoethylamine Hydrochloride,β-Mercaptoethylamine Hydrochloride,Thioethanolamine Hydrochloride,2-Aminoethanethiol Hydrochloride,Cysteamine HCl,Bekaptan Apoptosis , Others , Reactive Oxygen Species , Endogenous Metabolite , Autophagy
Cysteamine hydrochloride (Thioethanolamine Hydrochloride) is an agent for the treatment of nephropathic cystinosis and an antioxidant.
T2807 Caffeic Acid Lipoxygenase , Endogenous Metabolite , TRP/TRPV Channel
Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activities.
T2933 Wogonin Vogonin Apoptosis , Wnt/beta-catenin , CDK , Autophagy
Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.
T13092 Tauro-Obeticholic acid FXR
Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).
TQ0288 Hexahydrocurcumin Reactive Oxygen Species , ROS , COX
Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.
T1424 Ethynyl estradiol 17α-Ethynylestradiol,Ethinyl Estradiol Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
Ethynyl estradiol is a semisynthetic alkylated ESTRADIOL with a 17-alpha-ethinyl substitution. It has high estrogenic potency when administered orally, and is often used as the estrogenic component in ORAL CONTRACEPTIVES...
T3912 Saikosaponin B1 Others
Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro.
T5041 Faropenem sodium Antibacterial , Antibiotic
Faropenem sodium is an orally bioavailable penem antibiotic which can efficiently kill Mycobacterium tuberculosis.It treatment of tuberculosis and community-acquired pneumonia.
T6564 Leupeptin Hemisulfate Serine Protease , Cysteine Protease
Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor. It is an orally active, antioxidant and anti-inflammatory agent.
T4912 Jatrorrhizine chloride Yatrorhizine chloride,Neprotine chloride Others , 5-HT Receptor , OCT , Antibacterial , AChE
Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 h...
T2947 Indole-3-carbinol I3C,3-Indolemethanol,Indole-3-Methanol E1/E2/E3 Enzyme , NF-κB , Aryl Hydrocarbon Receptor , Endogenous Metabolite , p53
Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinase activation.
TN2429 Capsiate Antioxidant , TRP/TRPV Channel
Capsiate is an orally active TRPV1 agonist, a non-irritating capsaicin analog that acts as an antiallergic agent with anti-inflammatory, antioxidant, hypoglycemic, and inhibitory angiogenic activity.
T1126 Penicillin V Potassium Penicillin V potassium salt,Phenoxymethylpenicillin potassium salt Antibacterial , Antibiotic
Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is a broad-spectrum penicillin antibiotic used orally in the treatment of mild to moderate infections by susceptible gram-positive organisms.
T1261 Medroxyprogesterone Acetate Medroxyprogesterone 17-acetate,Provera,Metigestrona,NSC-26386,Farlutin,Medroxyprogesterone (acetate) Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , Androgen Receptor , Endogenous Metabolite
Medroxyprogesterone Acetate (Farlutin) is a synthetic progestin that is derived from 17-hydroxyprogesterone. It is a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been...
T3S2007 MRE-269 MRE 269,ACT-333679,MRE269 Prostaglandin Receptor
MRE-269 (ACT-333679) is an orally available and long-acting prostacyclin receptor agonist prodrug. MRE-269(ACT-333679) is used for the treatment of pulmonary arterial hypertension. MRE-269(ACT-333679) is an active metabo...
T11060 DMAPT Dimethylamino Parthenolide NF-κB
DMAPT (Dimethylamino Parthenolide) is a water-soluble analogue of Parthenolide (PTL). It is an orally active NF-κB inhibitor with an LD50 of 1.7 μM on primary acute myeloid leukemia cells.
TJS2216 Aurantiamide acetate Asperglaucide Cysteine Protease
Aurantiamide acetate (Asperglaucide) was isolated from the fermentation broth of Aspergillus penicilloides for the first time. Aurantiamide acetate is a selective and orally active cathepsin inhibitor. Aurantiamide aceta...
T1670 Lanatoside C Cedilanid,Ceglunate,Isolanid ATPase , Virus Protease , Autophagy
Lanatoside C (Ceglunate) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). Lanatoside C can be used orally or by the intrav...
T5544 2-Furoic acid Furan-2-carboxylic acid Anti-infection , ATP Citrate Lyase , Endogenous Metabolite , Acyltransferase
2-Furoic acid (Furan-2-carboxylic acid), an orally active selective human cathepsin K inhibitor, may have the therapeutic potential for the treatment of diseases characterized by excessive bone loss including osteoporosi...
T13506 3β-Ursodeoxycholic acid Isoursodeoxycholic acid
3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) is a bile acid. 3β-Ursodeoxycholic acid (administered orally has shown good tolerability and good intestinal absorption. 3β-Ursodeoxycholic acid can undergo enzymatic iso...
T16442 PCO371 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl- Thyroid hormone receptor(THR)
PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormon...
T0461 Berberine chloride Berberine hydrochloride,Benzodioxide,Natural Yellow 18 Reactive Oxygen Species , Topoisomerase , Antibacterial , Antibiotic , Autophagy
Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae and also found in many other plants. It is relatively toxic to parenterally but has been used orally for various fungal an...
T20643 Cefoxitin Rephoxitin,Cefoxitinum Cell wall , Antibacterial , Antibiotic
Cefoxitin (Rephoxitin) is a broad-spectrum, orally available second-generation cephalosporins antibiotic. Cefoxitin interferes with the synthesis of bacterial cell walls. Its activity profile includes Gram-negative and G...
T37152 3-Methyl-2-cyclopenten-1-one Endogenous Metabolite
3-Methyl-2-cyclopenten-1-one can be used as a food additive to improve the flavor of meat and meat products at 2-5 ppm. Addition of 3-Methyl-2-cyclopenten-1-one showed gastric cytoprotective activity when administered or...
T0883 Tramiprosate Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed Beta Amyloid , GABA Receptor
Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble Aβ and maintains it in a non-protofibrillar form.It is a GAB...
T5S1889 Yunaconitine Guayewuanine B Others
1. Yunaconitine (Guayewuanine B) has anti-inflammatory and analgesic actions. 2. Yunaconitine was shown to have anti-thermic effect in pyrexial rats when administered orally at a dose of 5 μg/kg. 3. Yunaconitine shows po...
T2220 2-Methoxyestradiol NSC-659853,2-MeOE2,2-ME2 Apoptosis , Reactive Oxygen Species , Microtubule Associated , Endogenous Metabolite , HIF , Autophagy
2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endotheli...
T15248 Estetrol Donesta Estrogen Receptor/ERR , Endogenous Metabolite
Estetrol(Donesta) is an orally available, selective modulator of the estrogen receptor, a naturally occurring estrogen synthesized by the human fetal liver during pregnancy.Estetrol has effects on the endometrium or cent...
T6491 (-)-(S)-Equol (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
(-)-(S)-Equol (4',7-Dihydroxyisoflavan) is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by human intestinal microflora, with potential chemoprotective a...
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Natural Products

Maohuoside A
TN2081
Synonym:
Target: MAPK
Nicotinamide riboside
T13795
Synonym:
Target: Sirtuin
macranthoidin A
T3858
Synonym:
Target: Others
N,N'-Dimethylthiourea
T40615
Synonym: DMTU
Target: Antioxidant
Dryocrassin ABBA
T4S1114
Synonym: Dryocrassin
Target: Influenza Virus, Antibacterial
Norisoboldine
T5S1895
Synonym: Laurelliptine,(+)-Laurelliptine
Target: MAPK, Adenosine Receptor
Safranal
TN2423
Synonym:
Target: Antioxidant
Prednisolone
T1560
Synonym: Predonine,Hydroretrocortine,Metacortandralone
Target: Glucocorticoid Receptor, Endogenous Metabolite
L-DOPA
T0848
Synonym: Levodopa,3,4-Dihydroxyphenylalanine
Target: Dopamine Receptor, Endogenous Metabolite
Topotecan
T5784
Synonym: NSC 609669,SKF 104864A
Target: Topoisomerase, Autophagy
Isotretinoin
T1611
Synonym: 13-cis-Retinoic acid
Target: Retinoid Receptor, Endogenous Metabolite, Autophagy
Abscisic Acid
T6368
Synonym: Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin)
Target: Others, Proton pump, Endogenous Metabolite
Nicotinamide riboside chloride
T6220
Synonym:
Target: Sirtuin, Endogenous Metabolite
Gentamicin sulfate
T1326
Synonym: SCH9724,Gentamycin sulfate,NSC-82261
Target: ribosome, DHFR, Antibacterial, Antibiotic
Novobiocin Sodium
T0974
Synonym: Albamycinsodium,Cathomycin,Albamycin
Target: Potassium Channel, DNA gyrase, Topoisomerase, Antibacterial, Antibiotic, ABC, Autophagy
NADH disodium salt
T5283
Synonym: Disodium NADH,NADH, disodium salt hydrate
Target: Others, Endogenous Metabolite
Se-Methylselenocysteine
T7727
Synonym: Se MSC,SeMCys,MSeC,Se-MSC,SeMSC
Target: BCL, IAP, Caspase
Fidaxomicin
T6194
Synonym: Tiacumicin B,OPT-80,Clostomicin B1,PAR-101
Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic
Succinic acid
T2719
Synonym: Asuccin,Amber acid,1,2-Ethanedicarboxylic acid,Wormwood acid,Butanedioic acid,1,4-Butandioic Acid
Target: Endogenous Metabolite
Amentoflavone
T3417
Synonym: Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin
Target: Apoptosis, P450, Phospholipase, Reactive Oxygen Species, Opioid Receptor, COX, Antibacterial, RSV, Antifungal
Rhoifolin
T2755
Synonym: Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside
Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy
Cysteamine hydrochloride
T6460
Synonym: 2-Mercaptoethylamine Hydrochloride,β-Mercaptoethylamine Hydrochloride,Thioethanolamine Hydrochloride,2-Aminoethanethiol Hydrochloride,Cysteamine HCl,Bekaptan
Target: Apoptosis, Others, Reactive Oxygen Species, Endogenous Metabolite, Autophagy
Caffeic Acid
T2807
Synonym:
Target: Lipoxygenase, Endogenous Metabolite, TRP/TRPV Channel
Wogonin
T2933
Synonym: Vogonin
Target: Apoptosis, Wnt/beta-catenin, CDK, Autophagy
Tauro-Obeticholic acid
T13092
Synonym:
Target: FXR
Hexahydrocurcumin
TQ0288
Synonym:
Target: Reactive Oxygen Species, ROS, COX
Ethynyl estradiol
T1424
Synonym: 17α-Ethynylestradiol,Ethinyl Estradiol
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite
Saikosaponin B1
T3912
Synonym:
Target: Others
Faropenem sodium
T5041
Synonym:
Target: Antibacterial, Antibiotic
Leupeptin Hemisulfate
T6564
Synonym:
Target: Serine Protease, Cysteine Protease
Jatrorrhizine chloride
T4912
Synonym: Yatrorhizine chloride,Neprotine chloride
Target: Others, 5-HT Receptor, OCT, Antibacterial, AChE
Indole-3-carbinol
T2947
Synonym: I3C,3-Indolemethanol,Indole-3-Methanol
Target: E1/E2/E3 Enzyme, NF-κB, Aryl Hydrocarbon Receptor, Endogenous Metabolite, p53
Capsiate
TN2429
Synonym:
Target: Antioxidant, TRP/TRPV Channel
Penicillin V Potassium
T1126
Synonym: Penicillin V potassium salt,Phenoxymethylpenicillin potassium salt
Target: Antibacterial, Antibiotic
Medroxyprogesterone Acetate
T1261
Synonym: Medroxyprogesterone 17-acetate,Provera,Metigestrona,NSC-26386,Farlutin,Medroxyprogesterone (acetate)
Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, Androgen Receptor, Endogenous Metabolite
MRE-269
T3S2007
Synonym: MRE 269,ACT-333679,MRE269
Target: Prostaglandin Receptor
DMAPT
T11060
Synonym: Dimethylamino Parthenolide
Target: NF-κB
Aurantiamide acetate
TJS2216
Synonym: Asperglaucide
Target: Cysteine Protease
Lanatoside C
T1670
Synonym: Cedilanid,Ceglunate,Isolanid
Target: ATPase, Virus Protease, Autophagy
2-Furoic acid
T5544
Synonym: Furan-2-carboxylic acid
Target: Anti-infection, ATP Citrate Lyase, Endogenous Metabolite, Acyltransferase
3β-Ursodeoxycholic acid
T13506
Synonym: Isoursodeoxycholic acid
Target:
PCO371
T16442
Synonym: 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-
Target: Thyroid hormone receptor(THR)
Berberine chloride
T0461
Synonym: Berberine hydrochloride,Benzodioxide,Natural Yellow 18
Target: Reactive Oxygen Species, Topoisomerase, Antibacterial, Antibiotic, Autophagy
Cefoxitin
T20643
Synonym: Rephoxitin,Cefoxitinum
Target: Cell wall, Antibacterial, Antibiotic
3-Methyl-2-cyclopenten-1-one
T37152
Synonym:
Target: Endogenous Metabolite
Tramiprosate
T0883
Synonym: Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed
Target: Beta Amyloid, GABA Receptor
Yunaconitine
T5S1889
Synonym: Guayewuanine B
Target: Others
2-Methoxyestradiol
T2220
Synonym: NSC-659853,2-MeOE2,2-ME2
Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated, Endogenous Metabolite, HIF, Autophagy
Estetrol
T15248
Synonym: Donesta
Target: Estrogen Receptor/ERR, Endogenous Metabolite
(-)-(S)-Equol
T6491
Synonym: (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite
Cat No. Product Name
L9850 Orally Active Compound Library

2484 compounds
A unique collection of 2484 of orally active compounds for high-throughput screening and high-content screening.
TargetMol