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SARS-CoV-2-IN-13

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Catalog No. T60919Cas No. 56961-10-5

SARS-CoV-2-IN-13 (compound 5) is an analogue of niclosamide, displaying greater stability in human plasma and liver S9 enzymes assay. It improves bioavailability and half-life when administered orally and is a potent SARS-CoV-2 inhibitor with an IC50 of 0.057 μM [1].

SARS-CoV-2-IN-13

SARS-CoV-2-IN-13

🥰Excellent
Purity: 98.15%
Catalog No. T60919Cas No. 56961-10-5
SARS-CoV-2-IN-13 (compound 5) is an analogue of niclosamide, displaying greater stability in human plasma and liver S9 enzymes assay. It improves bioavailability and half-life when administered orally and is a potent SARS-CoV-2 inhibitor with an IC50 of 0.057 μM [1].
Pack SizePriceAvailabilityQuantity
1 mg$31In Stock
5 mg$73In Stock
10 mg$118In Stock
25 mg$238In Stock
50 mg$353In Stock
100 mg$506In Stock
200 mg$686In Stock
1 mL x 10 mM (in DMSO)$80In Stock
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Purity:98.15%
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Product Introduction

Bioactivity
Description
SARS-CoV-2-IN-13 (compound 5) is an analogue of niclosamide, displaying greater stability in human plasma and liver S9 enzymes assay. It improves bioavailability and half-life when administered orally and is a potent SARS-CoV-2 inhibitor with an IC50 of 0.057 μM [1].
Chemical Properties
Molecular Weight327.12
FormulaC13H8Cl2N2O4
Cas No.56961-10-5
SmilesOc1ccc(Cl)cc1C(=O)Nc1ccc(c(Cl)c1)[N+]([O-])=O
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 112.5 mg/mL (343.9 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0570 mL15.2849 mL30.5698 mL152.8491 mL
5 mM0.6114 mL3.0570 mL6.1140 mL30.5698 mL
10 mM0.3057 mL1.5285 mL3.0570 mL15.2849 mL
20 mM0.1528 mL0.7642 mL1.5285 mL7.6425 mL
50 mM0.0611 mL0.3057 mL0.6114 mL3.0570 mL
100 mM0.0306 mL0.1528 mL0.3057 mL1.5285 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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