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SARS-CoV-2-IN-13

Catalog No. T60919 CAS 56961-10-5

SARS-CoV-2-IN-13 (compound 5) is an analogue of niclosamide. SARS-CoV-2-IN-13 is more stable than niclosamide in human plasma and liver S9 enzymes assay. SARS-CoV-2-IN-13 can improve bioavailability and half-life when administered orally. SARS-CoV-2-IN-13 is a potent SARS-CoV-2 inhibitor with an IC 50 of 0.057 μM [1].

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SARS-CoV-2-IN-13, CAS 56961-10-5

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	327.12
Formula	C13H8Cl2N2O4
CAS No.	56961-10-5

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 112.5 mg/mL (343.9 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Juang YP, et al. Design, synthesis and biological evaluations of niclosamide analogues against SARS-CoV-2. Eur J Med Chem. 2022 May 5;235:114295.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

SARS-CoV-2-IN-13 56961-10-5 Inhibitor inhibitor inhibit

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