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Oglemilast
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Oglemilast
Catalog No. T16379Cas No. 778576-62-8
Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast is an effective and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50: 0.5 nM for PDE4D3). Oglemilast has the potential for inflammatory airway diseases.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $36 | In Stock | |
| 5 mg | $88 | In Stock | |
| 10 mg | $151 | In Stock | |
| 25 mg | $232 | In Stock | |
| 50 mg | $297 | In Stock | |
| 100 mg | $433 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast is an effective and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50: 0.5 nM for PDE4D3). Oglemilast has the potential for inflammatory airway diseases. |
| In vitro | For the PDE 4B1 and PDE 4D3 reporter cell lines, Oglemilast has EC50s of 11.4 nM, 4.4 nM, respectively[3]. |
| Alias | GRC 3886 |
| Molecular Weight | 516.3 |
| Formula | C20H13Cl2F2N3O5S |
| Cas No. | 778576-62-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||
| Solubility Information | DMSO: 3.6 mg/mL (7 mM) | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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