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Ibezapolstat

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Catalog No. T10243Cas No. 1275582-97-2
Alias ACX-362E

ACX-362E is an orally available DNA polymerase IIIC (pol IIIC) inhibitor, acts as an antimicrobial agent to treat Gram-positive infections (MIC50: 2 μg/mL for C. difficile).

Ibezapolstat
Other Forms of Ibezapolstat:
Ibezapolstat hydrochlorideT601711275582-98-3
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Ibezapolstat

😃Good
Catalog No. T10243Alias ACX-362ECas No. 1275582-97-2
ACX-362E is an orally available DNA polymerase IIIC (pol IIIC) inhibitor, acts as an antimicrobial agent to treat Gram-positive infections (MIC50: 2 μg/mL for C. difficile).
Pack SizePriceAvailabilityQuantity
2 mg$1425 days
5 mg$2975 days
25 mg$9161-2 weeks
50 mg$1,1901-2 weeks
100 mg$1,8601-2 weeks
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Product Introduction

Bioactivity
Description
ACX-362E is an orally available DNA polymerase IIIC (pol IIIC) inhibitor, acts as an antimicrobial agent to treat Gram-positive infections (MIC50: 2 μg/mL for C. difficile).
Targets&IC50
DNA polymerase IIIC (C. difficile):0.325 μM (Ki)
AliasACX-362E
Chemical Properties
Molecular Weight423.3
FormulaC18H20Cl2N6O2
Cas No.1275582-97-2
Relative Density.1.56 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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