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Propiconazole
🥰Excellent
Catalog No. T20595Cas No. 60207-90-1
Alias Desmel, CGA-64250, CGA64250
Propiconazole (PRO) is an orally active brassinosteroid biosynthesis inhibitor and a triazole fungicide with antifungal activity.
Propiconazole
🥰Excellent
Catalog No. T20595Alias Desmel, CGA-64250, CGA64250Cas No. 60207-90-1
Propiconazole (PRO) is an orally active brassinosteroid biosynthesis inhibitor and a triazole fungicide with antifungal activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $30 | In Stock | |
| 10 mg | $39 | In Stock | |
| 25 mg | $60 | In Stock | |
| 50 mg | $84 | In Stock | |
| 100 mg | $122 | In Stock | |
| 200 mg | $177 | In Stock |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Propiconazole (PRO) is an orally active brassinosteroid biosynthesis inhibitor and a triazole fungicide with antifungal activity. |
| In vivo | Methods: Propiconazole (10, 75, 150 mg/kg, gavage, 14 days) was used to treat male Sprague-Dawley rats and male CD-1 mice to study the effects of propiconazole on hepatic cytochrome P450 gene expression and P450 enzyme activity in vivo; quantitative real-time RT-PCR was performed on rat liver RNA samples from animals treated with 150 mg/kg body weight/day. Results: Compared with the control, the mRNA of the following genes was significantly overexpressed: CYP1A2 (1.62-fold), CYP2B1 (10.8-fold), CYP3A1/CYP3A23 (2.78-fold), and CYP3A2 (1.84-fold); in mouse liver, propiconazole produced mRNA overexpression of Cyp2b10 (2.39-fold) and Cyp3a11 (5.19-fold); propiconazole significantly induced hexanoresorufin O-dealkylation (PROD) and methoxymethasone O-dealkylation (MROD) activities in rat and mouse livers at doses of 150 mg/kg and 75 mg/kg.[4] |
| Alias | Desmel, CGA-64250, CGA64250 |
| Molecular Weight | 342.22 |
| Formula | C15H17Cl2N3O2 |
| Cas No. | 60207-90-1 |
| Smiles | ClC1=CC=C(C(Cl)=C1)C2(OCC(O2)CCC)CN3N=CN=C3 |
| Relative Density. | 1.2700 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (233.77 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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