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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $45 | 5 days | |
1 mL x 10 mM (in DMSO) | $119 | 5 days |
Description | Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is a phenylbutazone derivative. It has an anti-inflammatory effect. Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis. |
In vitro | Oxyphenbutazone increases the anticancer efficiency of methotrexate (MTX) in Hep3B cells. Oxyphenbutazone has reparative effects in the hepatocytes. Oxyphenbutazone (2.5 -7.5 μM; 48 hours) co-treatment with (MTX, 0.25-1.0 μM) displays potential cytotoxicity against Hep3B cells[1]. |
In vivo | When co-treatment with MTX (5.0 or 2.5 mg/kg/week; i.p.), Oxyphenbutazone (70 mg/kg/week; p.o.; in two divided doses; for 13 weeks) has potential anticancer activity [1]. |
Molecular Weight | 324.37 |
Formula | C19H20N2O3 |
Cas No. | 129-20-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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