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PD 168568 dihydrochloride

PD 168568 dihydrochloride
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Purity:99.27%
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PD 168568 dihydrochloride

Catalog No. T12383Cas No. 1782532-06-2
PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).
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Pack SizePriceAvailabilityQuantity
1 mg$34In Stock
5 mg$66In Stock
10 mg$88In Stock
25 mg$199In Stock
50 mg$297In Stock
100 mg$433In Stock
500 mg$912In Stock
1 mL x 10 mM (in DMSO)$91In Stock
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Product Introduction

Bioactivity
Description
PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM).
In vitro
PD 168568 dihydrochloride has good selective for D4 receptor(Ki of 1842 nM for D2 receptor)[1].
In vivo
PD 168568 dihydrochloride inhibit amphetamine stimulated locomotor activity in the rat[1].
AliasPD 168568 (dihydrochloride)
Chemical Properties
Molecular Weight422.39
FormulaC22H29Cl2N3O
Cas No.1782532-06-2
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 55 mg/mL (130.21 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3675 mL11.8374 mL23.6748 mL118.3740 mL
5 mM0.4735 mL2.3675 mL4.7350 mL23.6748 mL
10 mM0.2367 mL1.1837 mL2.3675 mL11.8374 mL
20 mM0.1184 mL0.5919 mL1.1837 mL5.9187 mL
50 mM0.0473 mL0.2367 mL0.4735 mL2.3675 mL
100 mM0.0237 mL0.1184 mL0.2367 mL1.1837 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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