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Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 mg | $42 | In Stock | |
1 g | $50 | In Stock | |
5 g | $128 | In Stock | |
10 g | $158 | In Stock | |
1 mL x 10 mM (in DMSO) | $46 | In Stock |
Description | Doxepin hydrochloride (Aponal) is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors. |
Alias | Toruan, Novoxapin, Doxepin HCl, Aponal |
Molecular Weight | 315.837 |
Formula | C19H22ClNO |
Cas No. | 1229-29-4 |
Smiles | Cl.CN(C)CCC=C1c2ccccc2COc2ccccc12 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 60 mg/mL (189.97 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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