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SB399885
🥰Excellent
Catalog No. T19669Cas No. 402713-80-8
Alias SB399885 Hydrochloride, SB-399885, SB399885, SB 399885
SB399885 (SB 399885) is an effective, brain penetrant, and orally active antagonist of SR-6. It shows 200-fold selectivity for SR-6 over other serotonin receptors (pKi: 9.11, 8.81, and 9.02 for human recombinant, native rat, and native human SR-6 receptors, respectively).
SB399885
🥰Excellent
Purity: 98.94%
Catalog No. T19669Alias SB399885 Hydrochloride, SB-399885, SB399885, SB 399885Cas No. 402713-80-8
SB399885 (SB 399885) is an effective, brain penetrant, and orally active antagonist of SR-6. It shows 200-fold selectivity for SR-6 over other serotonin receptors (pKi: 9.11, 8.81, and 9.02 for human recombinant, native rat, and native human SR-6 receptors, respectively).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $89 | In Stock | |
| 5 mg | $178 | In Stock | |
| 10 mg | $266 | In Stock | |
| 25 mg | $439 | In Stock | |
| 50 mg | $592 | In Stock | |
| 100 mg | $833 | In Stock | |
| 200 mg | $1,120 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $218 | In Stock |
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Purity:98.94%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | SB399885 (SB 399885) is an effective, brain penetrant, and orally active antagonist of SR-6. It shows 200-fold selectivity for SR-6 over other serotonin receptors (pKi: 9.11, 8.81, and 9.02 for human recombinant, native rat, and native human SR-6 receptors, respectively). |
| Targets&IC50 | SR6 (human recombinant):9.11 (pKi), SR6 (native rat):8.81 (pKi), SR6 (native human):9.02 (pKi) |
| Alias | SB399885 Hydrochloride, SB-399885, SB399885, SB 399885 |
| Molecular Weight | 446.35 |
| Formula | C18H21Cl2N3O4S |
| Cas No. | 402713-80-8 |
| Smiles | O(C)C1=C(C=C(S(NC2=C(OC)C(Cl)=CC(Cl)=C2)(=O)=O)C=C1)N3CCNCC3 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/ml (123.22 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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