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Nithiamide

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Catalog No. T1108Cas No. 140-40-9
Alias CL-5279, Aminitrozole

Nithiamide (CL-5279) is an orally available antiprotozoan agent used in the treatment of vaginal trichomoniasis.

Nithiamide

Nithiamide

🥰Excellent
Purity: 100%
Catalog No. T1108Alias CL-5279, AminitrozoleCas No. 140-40-9
Nithiamide (CL-5279) is an orally available antiprotozoan agent used in the treatment of vaginal trichomoniasis.
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100 mg$29 In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
Nithiamide (CL-5279) is an orally available antiprotozoan agent used in the treatment of vaginal trichomoniasis.
In vivo
For both sensitive and metronidazole-resistant strains of Trichomonas vaginalis, Nithiamide showed sustained potent activity under both aerobic and anaerobic conditions.
AliasCL-5279, Aminitrozole
Chemical Properties
Molecular Weight187.18
FormulaC5H5N3O3S
Cas No.140-40-9
SmilesCC(=O)NC1=NC=C(S1)[N+]([O-])=O
Relative Density.1.598g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 35 mg/mL (186.99 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.3425 mL26.7123 mL53.4245 mL267.1226 mL
5 mM1.0685 mL5.3425 mL10.6849 mL53.4245 mL
10 mM0.5342 mL2.6712 mL5.3425 mL26.7123 mL
20 mM0.2671 mL1.3356 mL2.6712 mL13.3561 mL
50 mM0.1068 mL0.5342 mL1.0685 mL5.3425 mL
100 mM0.0534 mL0.2671 mL0.5342 mL2.6712 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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