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Edasalonexent
🥰Excellent
Catalog No. T15198Cas No. 1204317-86-1
Alias CAT-1004
Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor designed to improve Duchenne muscular dystrophy.
Edasalonexent
🥰Excellent
Purity: 100%
Catalog No. T15198Alias CAT-1004Cas No. 1204317-86-1
Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor designed to improve Duchenne muscular dystrophy.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $100 | In Stock | |
| 2 mg | $147 | In Stock | |
| 5 mg | $247 | In Stock | |
| 10 mg | $396 | In Stock | |
| 25 mg | $712 | In Stock | |
| 50 mg | $1,120 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $267 | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor designed to improve Duchenne muscular dystrophy. |
| In vitro | Edasalonexent effectively inhibits the pathogenic NF-κB subunit p65/RelA in vitro[3]. |
| In vivo | In vivo, Edasalonexent effectively improves the phenotype of mdx mice in terms of activity, muscle mass and function, injury, inflammation, fibrosis, and cardiac pathology associated with voluntary wheel running[3]. |
| Alias | CAT-1004 |
| Molecular Weight | 490.68 |
| Formula | C31H42N2O3 |
| Cas No. | 1204317-86-1 |
| Smiles | CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(=O)NCCNC(=O)c1ccccc1O |
| Relative Density. | 1.031 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (163.04 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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